1-Bromo-2-chloro-3-fluoro-4-methoxybenzene

Base Information

Chemical Name:1-Bromo-2-chloro-3-fluoro-4-methoxybenzene
CAS No.:909122-27-6
Molecular Formula:C₇H₅BrClFO
Molecular Weight:239.472
Hs Code.:
DSSTox Substance ID:DTXSID60697197
Wikidata:Q72452596
Mol file:909122-27-6.mol

Synonyms:1-Bromo-2-chloro-3-fluoro-4-methoxybenzene;909122-27-6;SCHEMBL13235170;AMY8632;DTXSID60697197;MFCD19440931;AKOS016012311;CS-0193044;FT-0737905;E91868;EN300-139021;Z1486003132

Suppliers and Price of 1-Bromo-2-chloro-3-fluoro-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Bromo-2-chloro-3-fluoro-4-methoxybenzene
500mg
$ 185.00

Crysdot
1-Bromo-2-chloro-3-fluoro-4-methoxybenzene 95+%
5g
$ 904.00

AOBChem
1-Bromo-2-chloro-3-fluoro-4-methoxybenzene 97%
1g
$ 276.00

American Custom Chemicals Corporation
1-BROMO-2-CHLORO-3-FLUORO-4-METHOXYBENZENE 95.00%
1G
$ 604.80

Alichem
1-Bromo-2-chloro-3-fluoro-4-methoxybenzene
5g
$ 902.88

Total 12 raw suppliers

Chemical Property of 1-Bromo-2-chloro-3-fluoro-4-methoxybenzene

Chemical Property:

Melting Point:49-50℃
Boiling Point:261℃
Flash Point:112℃
PSA：9.23000
Density:1.642
LogP:3.25020
Storage Temp.:2-8°C
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:237.91963
Heavy Atom Count:11
Complexity:136

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-2-chloro-3-fluoro-4-methoxybenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)Br)Cl)F
Uses 1-Bromo-2-chloro-3-fluoro-4-methoxybenzene is a synthetic intermediate in the synthesis of liquid crystal compound.

Technology Process of 1-Bromo-2-chloro-3-fluoro-4-methoxybenzene

There total 1 articles about 1-Bromo-2-chloro-3-fluoro-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 261762-56-5
1-chloro-2-fluoro-3-methoxy-benzene

: 909122-27-6
1-bromo-2-chloro-3-fluoro-4-methoxy-benzene

Guidance literature:: With bromine; In chlorobenzene; at 5 - 25 ℃; for 9h; Inert atmosphere;

Reference yield:

: 909122-27-6
1-bromo-2-chloro-3-fluoro-4-methoxy-benzene

: 2-chloro-3-fluoro-4-methoxybenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium / tetrahydrofuran / 2.5 h / 30 °C

1.2: 1.5 h / 0 °C

2.1: sulfuric acid / 8 h / 65 °C / Reflux

With sulfuric acid; magnesium; In tetrahydrofuran;