3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine

Base Information

Chemical Name:3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine
CAS No.:1190309-71-7
Molecular Formula:C7H4BrFN2
Molecular Weight:215.025
Hs Code.:
Mol file:1190309-71-7.mol

Synonyms:3-broMo-5-fluoro-1H-pyrrolo[2,3-b]pyridine;3-broMo-5-fluoro-1H-pyrrolo[2;1H-Pyrrolo[2,3-b]pyridine, 3-broMo-5-fluoro-

Suppliers and Price of 3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine
500mg
$ 220.00

SynChem
3-Bromo-5-fluoro-7-azaindole 95+%
5 g
$ 1750.00

SynChem
3-Bromo-5-fluoro-7-azaindole 95+%
1 g
$ 450.00

Matrix Scientific
3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine
5g
$ 1006.00

Matrix Scientific
3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine
1g
$ 330.00

Chemenu
3-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine 95%+
1g
$ 159.00

Chemenu
3-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine 95%+
250mg
$ 84.00

Chemenu
3-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine 95%+
5g
$ 800.00

Chemenu
3-bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine 95%+
10g
$ 1213.00

American Custom Chemicals Corporation
3-BROMO-5-FLUORO-7-AZAINDOLE 95.00%
500MG
$ 924.00

Total 18 raw suppliers

Chemical Property of 3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

PSA：28.68000
LogP:2.46450
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine

There total 4 articles about 3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 866319-00-8
5-fluoro-1H-pyrrolo[2,3‐b]pyridine

: 1190309-71-7
3-bromo-5-fluoro-1H-pyrrolo-[2,3-b]pyridine

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/cmdc.202100144

Reference yield: 61.0%

: 866319-01-9
5-fluoro-3-(2-trimethylsilylethynyl)pyridine-2-amine

: 1190309-71-7
3-bromo-5-fluoro-1H-pyrrolo-[2,3-b]pyridine

Guidance literature:: With 1-methyl-pyrrolidin-2-one; potassium tert-butylate; at 20 - 130 ℃; for 2h;

Reference yield:

: 823218-51-5
5-fluoro-3-iodo-pyridin-2-amine

: 1190309-71-7
3-bromo-5-fluoro-1H-pyrrolo-[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 2 h / 50 °C / Inert atmosphere

2: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 2 h / 130 °C

3: N-Bromosuccinimide / N,N-dimethyl-formamide / 2 h / 0 °C

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; copper(l) iodide; potassium tert-butylate; triethylamine; In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide;