Welcome to LookChem.com Sign In|Join Free

CAS

  • or
5-Fluoro-3-iodo-pyridin-2-ylamine is a chemical compound that belongs to the category of organic compounds known as halopyridines, characterized by the presence of a halogen atom bonded to a pyridine ring. It has a molecular formula of C5H3FIN3. 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE's properties, which include both fluorine and iodine substituents, make it an important compound in chemical synthesis and pharmaceutical research due to its potential as a building block for more complex chemical structures. The specific information on its toxicity or safety is not well documented, hence it needs to be handled with general chemical safety protocols.

823218-51-5 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 823218-51-5 Structure
  • Basic information

    1. Product Name: 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE
    2. Synonyms: 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE;2-Amino-3-iodo-5-fluoropyridine;5-Fluoro-3-iodo-2-aMinopyridine;2-PyridinaMine, 5-fluoro-3-iodo-
    3. CAS NO:823218-51-5
    4. Molecular Formula: C5H4FIN2
    5. Molecular Weight: 238.0015332
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 823218-51-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 269℃
    3. Flash Point: 117℃
    4. Appearance: /
    5. Density: 2.139
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 2.22±0.49(Predicted)
    10. CAS DataBase Reference: 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE(823218-51-5)
    12. EPA Substance Registry System: 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE(823218-51-5)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 823218-51-5(Hazardous Substances Data)

823218-51-5 Usage

Uses

Used in Chemical Synthesis:
5-Fluoro-3-iodo-pyridin-2-ylamine is used as a building block for the synthesis of more complex chemical structures, particularly in the field of organic chemistry. Its unique combination of fluorine and iodine substituents allows for versatile reactions and the creation of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-Fluoro-3-iodo-pyridin-2-ylamine is used as a key intermediate in the development of new drugs. Its structural properties make it a valuable component in the design and synthesis of potential therapeutic agents, contributing to the advancement of medicinal chemistry.
Used in Material Science:
5-Fluoro-3-iodo-pyridin-2-ylamine may also find applications in material science, where its unique chemical properties could be utilized in the development of new materials with specific characteristics, such as improved stability or reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 823218-51-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,3,2,1 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 823218-51:
(8*8)+(7*2)+(6*3)+(5*2)+(4*1)+(3*8)+(2*5)+(1*1)=145
145 % 10 = 5
So 823218-51-5 is a valid CAS Registry Number.

823218-51-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-fluoro-3-iodopyridin-2-amine

1.2 Other means of identification

Product number -
Other names 2-Amino-5-fluoro-3-iodopyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:823218-51-5 SDS

823218-51-5Relevant articles and documents

ANTI-INFLUENZA VIRUS PYRIMIDINE DERIVATIVE

-

Paragraph 0116; 0117, (2021/02/05)

The present invention discloses a class of anti-influenza virus compounds, and the use thereof in the preparation of a drug for treating diseases associated with influenza viruses. In particular, the present invention discloses a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION

-

Paragraph 00349, (2020/02/16)

Provided herein are compounds of Formula A, B or C that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.

PYRROLOPYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF INFLUENZA VIRUS REPLICATION

-

Paragraph 00369, (2018/11/22)

Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient a safe and effective amount of a compound represented by any of Formulas l-lll, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a safe and effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site

Burnett, James C.,Lim, Chaemin,Peyser, Brian D.,Samankumara, Lalith P.,Kovaliov, Marina,Colombo, Raffaele,Bulfer, Stacie L.,LaPorte, Matthew G.,Hermone, Ann R.,McGrath, Connor F.,Arkin, Michelle R.,Gussio, Rick,Huryn, Donna M.,Wipf, Peter

supporting information, p. 4096 - 4114 (2017/07/10)

The turnstile motion of two neighboring threonines sets up a dynamic side chain interplay that can accommodate both polar and apolar ligands in a small molecule allosteric protein binding site. A computational model based on SAR data and both X-ray and cr

METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION

-

Paragraph 0264; 0265, (2016/12/01)

A method of preparing a compound of Formula (I) or a pharmaceutically acceptable salt thereof comprises: (a) reacting Compound (1) or (b) a pharmaceutically acceptable salt thereof with Compound (2) in the presence of water, an organic solvent, a base, an

METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION

-

Paragraph 0301-0302, (2015/06/03)

A method of preparing Compound (1) or a pharmaceutically acceptable salt thereof: comprises: (a) reacting Compound (X): a pharmaceutically acceptable salt thereof with Compound (Y): in the presence of a palladium catalyst and a carbonate or phosphate base

1, 7 - DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER

-

Page/Page column 83-84, (2011/07/07)

The invention relates to 1, 7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chk 1) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

N-(amino-heteroaryl)-1H-pyrrolopyridine-2-carboxamides derivatives preparation thereof and their use in therapy

-

Page/Page column 17, (2010/03/04)

The invention relates to compounds of the general formula (I): Wherein X, Y, Z, Z1, Z2, Z3, Z4 and n are as defined herein. The invention also relates to a method for making the same and to the use thereof in th

TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE

-

Page/Page column 24, (2009/03/07)

The invention concerns tricyclic N-heteroarylcarboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention also concerns a method of preparing the compounds and their therapeutic use.

Derivatives of pyrrolopyridine-2-carboxamides, preparation thereof and therapeutic application thereof

-

Page/Page column 5, (2009/12/23)

The invention relates to compounds of formula (I): Wherein n, the pyrrolopyridine core, X, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 823218-51-5