1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)-

Base Information

Chemical Name:1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)-
CAS No.:947144-28-7
Molecular Formula:C₉H₈F₃NO₄
Molecular Weight:251.162
Hs Code.:
Mol file:947144-28-7.mol

Synonyms:Ethyl 2,4-dihydroxy-6-(trifluoromethyl)nicotinate;2,4-Dihydroxy-6-trifluoromethyl-nicotinic acid ethyl ester;

Suppliers and Price of 1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2,4-dihydroxy-6-(trifluoromethyl)nicotinate 95+%
1g
$ 772.00

ChemScene
Ethyl4-hydroxy-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylate
5g
$ 1902.00

ChemScene
Ethyl4-hydroxy-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylate
1g
$ 634.00

Chemenu
ethyl2,4-dihydroxy-6-(trifluoromethyl)nicotinate 95%
1g
$ 729.00

American Custom Chemicals Corporation
ETHYL-2,4-DIHYDROXY-6-(TRIFLUOROMETHYL)NICOTINATE 95.00%
5MG
$ 501.53

Alichem
Ethyl2,4-dihydroxy-6-(trifluoromethyl)nicotinate
1g
$ 621.72

AK Scientific
Ethyl2,4-dihydroxy-6-(trifluoromethyl)nicotinate
1g
$ 843.00

Total 6 raw suppliers

Chemical Property of 1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)-

Chemical Property:

PSA：79.65000
LogP:1.68830
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2,4-dihydroxy-6-(trifluoromethyl)nicotinate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)-

There total 4 articles about 1H-BenziMidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoroMethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 947144-30-1
3-(2-ethoxycarbonylacetylamino)-4,4,4-trifluorobut-2-enoic acid ethyl ester

: 947144-28-7
4-hydroxy-2-oxo-6-trifluoromethyl-1,2-dihydropyridine-3-carboxylic acid ethyl ester

Guidance literature:: With potassium tert-butylate; In ethanol; at 20 - 70 ℃; for 2h; Inert atmosphere;

Reference yield: 63.0%

: 36239-09-5
ethyl chlorocarbonylacetate

: 372-29-2,141860-78-8
ethyl 3-amino-4,4,4-trifluoro-2-butenoate

: 947144-28-7
4-hydroxy-2-oxo-6-trifluoromethyl-1,2-dihydropyridine-3-carboxylic acid ethyl ester

Guidance literature:: ethyl chlorocarbonylacetate; ethyl 3-amino-4,4,4-trifluoro-2-butenoate; With pyridine; In dichloromethane; at 20 - 30 ℃; for 68.8333h;

With potassium tert-butylate; In ethanol; at 20 - 70 ℃;
DOI:10.1021/op200021a

Reference yield:

: 947144-30-1
3-(2-ethoxycarbonylacetylamino)-4,4,4-trifluorobut-2-enoic acid ethyl ester

: 947144-28-7
ethyl 2,4-dihydroxy-6-(trifluoromethyl)nicotinate

Guidance literature:: 3-(2-ethoxycarbonylacetylamino)-4,4,4-trifluorobut-2-enoic acid ethyl ester; With potassium tert-butylate; In ethanol; at 60 - 80 ℃; for 4h;

With citric acid; In water;