1-(1-BroMovinyl)-2-Methoxybenzene

Base Information

• Chemical Name: 1-(1-BroMovinyl)-2-Methoxybenzene
• CAS No.: 203176-35-6
• Molecular Formula: C9H9BrO
• Molecular Weight: 213.07
• Mol file: 203176-35-6.mol

Synonyms:1-(1-BroMovinyl)-2-Methoxybenzene;1-(1-Bromoethenyl)-2-methoxybenzene;Benzene, 1-(1-bromoethenyl)-2-methoxy-

Chemical Property of 1-(1-BroMovinyl)-2-Methoxybenzene

Chemical Property:

Purity/Quality:

99.3% ^*data from raw suppliers

1-(1-Bromovinyl)-2-methoxybenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-BroMovinyl)-2-Methoxybenzene

There total 2 articles about 1-(1-BroMovinyl)-2-Methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethynyl-2-methoxybenzene (767-91-9) + 1,1-dibromomethane (74-95-3) → 1-(1-bromovinyl)-2-methoxybenzene (203176-35-6)

Guidance literature:

In N,N-dimethyl-aniline; at 120 ℃; for 12h; Schlenk technique;

DOI:10.1021/acs.orglett.1c02208

Reference yield:

2-Methoxyacetophenone (579-74-8) → 1-(1-bromovinyl)-2-methoxybenzene (203176-35-6)

Guidance literature:

With triphenyl phosphite; bromine; triethylamine; In dichloromethane; at -78 ℃; for 20h; Inert atmosphere; Reflux;

DOI:10.1039/C8CC04285C

Reference yield: 81.0%

1-(1-bromovinyl)-2-methoxybenzene (203176-35-6) + Benzenesulfinic acid (618-41-7) → 1-(2-methoxyphenyl)-2-(phenylsulfonyl)-1-ethanone (1448165-00-1)

Guidance literature:

With pyridine; oxygen; In tetrahydrofuran; at 20 ℃; for 5h; under 760.051 Torr;

DOI:10.1039/c4ra17106c

upstream raw materials:

2-Methoxyacetophenone

1-ethynyl-2-methoxybenzene

1,1-dibromomethane

Downstream raw materials:

1-(2-methoxyphenyl)-2-(phenylsulfonyl)-1-ethanone

ethyl 4-(2-methoxyphenyl)-4-oxobutanoate

Refernces

• 1、 Xu, Ming-Hui,Dai, Kun-Long,Tu, Yong-Qiang,Zhang, Xiao-Ming,Zhang, Fu-Min,Wang, Shao-Hua. "A catalytic allylic cation-induced intermolecular allylation-semipinacol rearrangement". supporting information. p. 7685 - 7688. Retrieved 2018/07/15.