1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER

Base Information

Chemical Name:1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER
CAS No.:18450-28-7
Molecular Formula:C13H13NO3
Molecular Weight:231.251
Hs Code.:2933990090
Mol file:18450-28-7.mol

Synonyms:1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER;Ethyl 3-Formyl-1-methyl-1H-indole-2-carboxylate;

Suppliers and Price of 1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl3-Formyl-1-methyl-1H-indole-2-carboxylate
1g
$ 165.00

Labseeker
1H-INDOLE-2-CARBOXYLICACID,3-FORMYL-1-METHYL-,ETHYLESTER 95
1g
$ 1233.00

American Custom Chemicals Corporation
1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER 95.00%
5MG
$ 500.76

Total 5 raw suppliers

Chemical Property of 1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER

Chemical Property:

PSA：48.30000
LogP:2.16750

Purity/Quality:

99% ^*data from raw suppliers

Ethyl3-Formyl-1-methyl-1H-indole-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Ethyl 3-Formyl-1-methyl-1H-indole-2-carboxylate has been used as a reactant for the synthesis of pyridazino[4,5-b]indole derivatives as inhibitors of monamine oxidase

Technology Process of 1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER

There total 6 articles about 1H-INDOLE-2-CARBOXYLIC ACID,3-FORMYL-1-METHYL-,ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 18450-27-6
ethyl 3-formyl-1H-indole-2-carboxylate

: 74-88-4
methyl iodide

: 18450-28-7
ethyl 3-formyl-1-methyl-1H-indole-2-carboxylate

Guidance literature:: With potassium carbonate; In acetone;
DOI:10.1055/s-0031-1290380

Reference yield: 95.2%

: 18450-24-3
ethyl N-methylindole-2-carboxylate

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 18450-28-7
ethyl 3-formyl-1-methyl-1H-indole-2-carboxylate

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; at -5 - 0 ℃; Inert atmosphere;

ethyl N-methylindole-2-carboxylate; at 60 ℃; for 2h; regioselective reaction; Inert atmosphere;
DOI:10.1002/jhet.2403

Reference yield: 75.0%

: 18450-27-6
ethyl 3-formyl-1H-indole-2-carboxylate

: 18450-28-7
ethyl 3-formyl-1-methyl-1H-indole-2-carboxylate

Guidance literature:: ethyl 3-formyl-1H-indole-2-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h; Inert atmosphere;

methyl halide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.5h;
DOI:10.1016/j.tetasy.2011.02.020