7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide

Base Information

Chemical Name:7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide
CAS No.:354570-65-3
Molecular Formula:C11H13N3O2
Molecular Weight:219.24000
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00452621
Wikidata:Q82273367
Mol file:354570-65-3.mol

Synonyms:7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide;354570-65-3;SCHEMBL7224237;DTXSID00452621;3,4-DIFLUOROPHENYLMAGNESIUMBROMIDE;1h-indazole-3-carboxamide,7-methoxy-n,n-dimethyl-

Suppliers and Price of 7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-METHOXY-N,N-DIMETHYL-1H-INDAZOLE-3-CARBOXAMIDE 95.00%
5MG
$ 503.92

AccelPharmtech
7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide 97.00%
25G
$ 9110.00

AccelPharmtech
7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide 97.00%
5G
$ 4850.00

AccelPharmtech
7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide 97.00%
1G
$ 2820.00

Total 6 raw suppliers

Chemical Property of 7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide

Chemical Property:

PSA：58.22000
LogP:1.27330
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.100776666
Heavy Atom Count:16
Complexity:270

Purity/Quality:

97% ^*data from raw suppliers

7-METHOXY-N,N-DIMETHYL-1H-INDAZOLE-3-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=NNC2=C1C=CC=C2OC

Technology Process of 7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide

There total 4 articles about 7-methoxy-N,N-dimethyl-1H-indazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 354573-95-8
[3-methoxy-2-(tert-butyloxycarbonylamino)]phenylacetic acid dimethylacetamide

: 354570-65-3
7-methoxy-3-dimethylamidoindazole

Guidance literature:: With acetic acid; sodium nitrite; at 95 ℃;
DOI:10.1021/jm020329q

Reference yield:

: 545424-34-8
3-methoxy-2-(tert-butyloxycarbonylamino)toluene

: 354570-65-3
7-methoxy-3-dimethylamidoindazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-BuLi / tetrahydrofuran / -40 - -10 °C

1.2: 80 percent / tetrahydrofuran

2.1: 78 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole; diisopropylethylamine / dimethylformamide / 48 h / 20 °C

3.1: 82 percent / aq. AcOH; NaNO₂ / 95 °C

With n-butyllithium; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium nitrite; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm020329q

Reference yield:

: 50868-73-0
2-methoxy-6-methylbenzeneamine

: 354570-65-3
7-methoxy-3-dimethylamidoindazole

Guidance literature:: Multi-step reaction with 4 steps

1.1: 80 percent / tetrahydrofuran / 24 h / Heating

2.1: n-BuLi / tetrahydrofuran / -40 - -10 °C

2.2: 80 percent / tetrahydrofuran

3.1: 78 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole; diisopropylethylamine / dimethylformamide / 48 h / 20 °C

4.1: 82 percent / aq. AcOH; NaNO₂ / 95 °C

With n-butyllithium; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium nitrite; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm020329q