1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)-

Base Information

Chemical Name:1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)-
CAS No.:80443-18-1
Molecular Formula:C13H12N4
Molecular Weight:224.265
Hs Code.:

Synonyms:4-benzylamino-1H-imidazo[4,5-c]-pyridine;Benzyl-(1H-imidazo[4,5-c]pyridin-4-yl)-amine;4-(benzylamino)-1H-imidazo[4,5-c]pyridine;

Suppliers and Price of 1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)-

Chemical Property:

Melting Point:60 - 64 °C
PSA：53.60000
LogP:2.64300

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)-

There total 8 articles about 1H-Imidazo[4,5-c]pyridin-4-amine, N-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: N₂-benzylpyridine-2,3,4-triamine

: 122-51-0
orthoformic acid triethyl ester

: 3-benzyl-3H-imidazo[4,5-b]pyridin-7-amine

: 80443-18-1
N-benzyl-1H-imidazo[4,5-c]pyridin-4-amine

Guidance literature:: With hydrogenchloride; In water; at 20 ℃; for 14h; Inert atmosphere;
DOI:10.1016/j.bmc.2016.09.055

Reference yield: 31.5%

: 2770-01-6
4-chloro-1H-imidazo[4,5-c]pyridine

: 100-46-9
benzylamine

: 80443-18-1
N-benzyl-1H-imidazo[4,5-c]pyridin-4-amine

Guidance literature:: In water; for 96h; Heating;
DOI:10.1021/jm00151a022

Reference yield:

: 109-09-1
2-chloropyridine

: 3-benzyl-3H-imidazo[4,5-b]pyridin-7-amine

: 80443-18-1
N-benzyl-1H-imidazo[4,5-c]pyridin-4-amine

Guidance literature:: Multi-step reaction with 7 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C

2: nitric acid; sulfuric acid / 90 °C

3: iron; hydrogenchloride / ethanol; water / Reflux

4: nitric acid; sulfuric acid / 0 - 75 °C

5: ethanol / 2 h / Reflux

6: hydrogen; palladium 10% on activated carbon / ethanol / 4 h / 20 °C / 1706.63 Torr

7: hydrogenchloride / water / 14 h / 20 °C / Inert atmosphere

With hydrogenchloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; nitric acid; iron; 3-chloro-benzenecarboperoxoic acid; In ethanol; dichloromethane; water;
DOI:10.1016/j.bmc.2016.09.055