TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE

Base Information

• Chemical Name: TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE
• CAS No.: 220913-43-9
• Molecular Formula: C11H15FN2O2
• Molecular Weight: 226.251
• Mol file: 220913-43-9.mol

Synonyms:4-tert-Butyloxycarbonylamino-3-fluoroaniline;AB3291;

Chemical Property of TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE

Chemical Property:

• PSA: 67.84000
• LogP: 3.34970

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl4-Amino-2-fluorophenylcarbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE

There total 5 articles about TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

tert-butyl (2-fluoro-4-nitrophenyl)carbamate (220913-42-8) → tert-butyl N-(4-amino-2-fluorophenyl)carbamate (220913-43-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃;

Reference yield:

tert-butyl N-(3-fluoro-4-nitrophenyl)carbamate (658700-15-3) → tert-butyl N-(4-amino-2-fluorophenyl)carbamate (220913-43-9)

Guidance literature:

With iron; for 65h; Reflux;

DOI:10.1016/j.ejmech.2019.07.038

Reference yield:

2-fluoro-4-nitroaniline (369-35-7) → tert-butyl N-(4-amino-2-fluorophenyl)carbamate (220913-43-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 20 °C

2: palladium 10% on activated carbon; ammonium formate / isopropyl alcohol; water / 2 h / 20 °C

With dmap; palladium 10% on activated carbon; ammonium formate; triethylamine; In dichloromethane; water; isopropyl alcohol;

upstream raw materials:

2-fluoro-4-nitroaniline

3-fluoro-4-nitroaniline

tert-butyl N-(3-fluoro-4-nitrophenyl)carbamate

tert-butyl (2-fluoro-4-nitrophenyl)carbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220913-43-9 TERT-BUTYL 4-AMINO-2-FLUOROPHENYLCARBAMATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send