6-Fluoro-1H-pyrrolo[3,2-b]pyridine

Base Information

Chemical Name:6-Fluoro-1H-pyrrolo[3,2-b]pyridine
CAS No.:1190320-33-2
Molecular Formula:C7H5FN2
Molecular Weight:136.129
Hs Code.:2933998090
European Community (EC) Number:860-113-3
DSSTox Substance ID:DTXSID40696663
Wikidata:Q82626335
Mol file:1190320-33-2.mol

Synonyms:6-Fluoro-1H-pyrrolo[3,2-b]pyridine;1190320-33-2;6-FLUORO-4-AZAINDOLE;MFCD12962608;1H-Pyrrolo[3,2-b]pyridine, 6-fluoro-;SCHEMBL15058364;AMY9899;DTXSID40696663;CVGJTKLSMRMEOX-UHFFFAOYSA-N;AKOS016011455;CS-W022496;PB15121;DS-15583;SY034660;EN300-395747;P11534;A892700;Z1255388239

Suppliers and Price of 6-Fluoro-1H-pyrrolo[3,2-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
10mg
$ 45.00

SynQuest Laboratories
6-Fluoro-1H-pyrrolo[3,2-b]pyridine 97%
250 mg
$ 280.00

SynQuest Laboratories
6-Fluoro-1H-pyrrolo[3,2-b]pyridine 97%
1 g
$ 680.00

Matrix Scientific
6-Fluoro-4-azaindole 95+%
1g
$ 1073.00

Crysdot
6-Fluoro-1H-pyrrolo[3,2-b]pyridine 95%
1g
$ 391.00

Crysdot
6-Fluoro-1H-pyrrolo[3,2-b]pyridine 95%
5g
$ 1174.00

Chemenu
6-fluoro-1H-pyrrolo[3,2-b]pyridine 95%+
5g
$ 1807.00

Chemenu
6-fluoro-1H-pyrrolo[3,2-b]pyridine 95%+
1g
$ 488.00

Chemenu
6-fluoro-1H-pyrrolo[3,2-b]pyridine 95%+
100mg
$ 112.00

Chemenu
6-fluoro-1H-pyrrolo[3,2-b]pyridine 95%+
250mg
$ 202.00

Total 26 raw suppliers

Chemical Property of 6-Fluoro-1H-pyrrolo[3,2-b]pyridine

Chemical Property:

Boiling Point:277.6±20.0 °C(Predicted)
PKA:14.06±0.40(Predicted)
PSA：28.68000
Density:1.370±0.06 g/cm3(Predicted)
LogP:1.70200
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:136.04367633
Heavy Atom Count:10
Complexity:129

Purity/Quality:

99%, ^*data from raw suppliers

6-Fluoro-1H-pyrrolo[3,2-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=C1N=CC(=C2)F

Technology Process of 6-Fluoro-1H-pyrrolo[3,2-b]pyridine

There total 1 articles about 6-Fluoro-1H-pyrrolo[3,2-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 884495-03-8
3-amino-2-bromo-5-fluoropyridine

: 1190320-33-2
6-fluoro-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium hydride; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;

Reference yield: 80.0%

: 1190320-33-2
6-fluoro-1H-pyrrolo[3,2-b]pyridine

: 98-59-9
p-toluenesulfonyl chloride

: 1445856-42-7
6-fluoro-1-tosyl-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: 6-fluoro-1H-pyrrolo[3,2-b]pyridine; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 0.5h;

p-toluenesulfonyl chloride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃;

Reference yield:

: 1190320-33-2
6-fluoro-1H-pyrrolo[3,2-b]pyridine

: 16470-09-0
2-methyl-4-chlorobenzyl chloride

: 1-(4-chloro-2-methylbenzyl)-6-fluoro-1H-pyrrolo[3,2-b]pyridine

Guidance literature:: 6-fluoro-1H-pyrrolo[3,2-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

2-methyl-4-chlorobenzyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.16667h; Inert atmosphere;
DOI:10.1021/acsinfecdis.1c00171