3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

Base Information

Chemical Name:3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS No.:1227911-51-4
Molecular Formula:C14H19BN2O2
Molecular Weight:258.128
Hs Code.:2933990090
Mol file:1227911-51-4.mol

Synonyms:3-methyl-6-indazoleboronic acid pinacol ester;3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole;3-METHYL-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-INDAZOLE;3-METHYLINDAZOLE-6-BORONIC ACID PINACOL ESTER;

Suppliers and Price of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
100mg
$ 90.00

TRC
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
50mg
$ 45.00

Synthonix
3-Methylindazole-6-boronicacidpinacolester 97.0%
10g
$ 1360.00

Synthonix
3-Methylindazole-6-boronicacidpinacolester 97.0%
1g
$ 260.00

SynQuest Laboratories
3-Methylindazole-6-boronic acid, pinacol ester
250 mg
$ 199.00

SynQuest Laboratories
3-Methylindazole-6-boronic acid, pinacol ester
1 g
$ 690.00

Crysdot
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 95+%
5g
$ 2057.00

Crysdot
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 95+%
1g
$ 597.00

Chemcia Scientific
3-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole 95%
10 G
$ 1015.00

AOBChem
3-Methylindazole-6-boronicacidpinacolester 97%
10g
$ 1120.00

Total 13 raw suppliers

Chemical Property of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

Chemical Property:

PSA：47.14000
LogP:2.17050

Purity/Quality:

99%, ^*data from raw suppliers

3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

There total 4 articles about 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 7746-27-2
6-bromo-3-methyl-1 H-indazole

: 73183-34-3
bis(pinacol)diborane

: 1227911-51-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1-indazole

Guidance literature:: With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; dichloromethane; at 80 ℃; for 12.5h; Inert atmosphere;

Reference yield:

: 57848-46-1
4-bromo-2-fluorobenzaldehyde

: 1227911-51-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1-indazole

Guidance literature:: Multi-step reaction with 4 steps

1: diethyl ether / 12 h / 20 °C / Cooling with ice

2: dipyridinium dichromate / N,N-dimethyl-formamide / 12 h / 20 °C

3: hydrazine hydrate / ethylene glycol / 12 h / 165 °C

4: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dichloromethane; 1,4-dioxane / 12.5 h / 80 °C / Inert atmosphere

With dipyridinium dichromate; potassium acetate; hydrazine hydrate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; diethyl ether; dichloromethane; ethylene glycol; N,N-dimethyl-formamide;

Reference yield:

: 625446-22-2
4-bromo-2-fluoroacetophenone

: 1227911-51-4
3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1-indazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethylene glycol / 12 h / 165 °C

2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dichloromethane; 1,4-dioxane / 12.5 h / 80 °C / Inert atmosphere

With potassium acetate; hydrazine hydrate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; dichloromethane; ethylene glycol;