2-Chlorothiazolo[4,5-c]pyridine

Base Information

• Chemical Name: 2-Chlorothiazolo[4,5-c]pyridine
• CAS No.: 884860-63-3
• Molecular Formula: C6H3ClN2S
• Molecular Weight: 170.61900
• Hs Code.: 2934999090
• Mol file: 884860-63-3.mol

Synonyms:2-chloro-[1,3]thiazolo[4,5-c]pyridine;

Chemical Property of 2-Chlorothiazolo[4,5-c]pyridine

Chemical Property:

• Vapor Pressure: 0.006mmHg at 25°C
• Boiling Point: 281.6±13.0 °C(Predicted)
• PKA: 0.71±0.50(Predicted)
• PSA: 54.02000
• Density: 1.531±0.06 g/cm3(Predicted)
• LogP: 2.34470
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chlorothiazolo[4,5-c]pyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chlorothiazolo[4,5-c]pyridine

There total 3 articles about 2-Chlorothiazolo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

thiazolo[4,5-c]pyridine-2(3H)-thione (65128-66-7) → 2-chlorothiazolo[4,5-c]pyridine (884860-63-3)

Guidance literature:

With sulfuryl dichloride; at 18 - 25 ℃;

Reference yield: 22.15%

thiazolo[4,5-c]pyridine-2-ylamine (89786-54-9) → 2-chlorothiazolo[4,5-c]pyridine (884860-63-3)

Guidance literature:

With tert.-butylnitrite; copper dichloride; In acetonitrile; at 60 ℃; for 1.5h;

Reference yield:

→ 2-chlorothiazolo[4,5-c]pyridine (884860-63-3)

Guidance literature:

upstream raw materials:

thiazolo[4,5-c]pyridine-2(3H)-thione

thiazolo[4,5-c]pyridine-2-ylamine

Refernces

• 1、 -. "NOVEL HETEROARYL-AMINO DERIVATIVES". Page/Page column 32. . Retrieved 2013/05/09.
• 2、 -. "PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY". Page/Page column 65. . Retrieved 2010/11/08.