1,3-Dichloro-1,1-difluoropropane

Base Information

• Chemical Name: 1,3-Dichloro-1,1-difluoropropane
• CAS No.: 819-00-1
• Molecular Formula: C3H4Cl2F2
• Molecular Weight: 148.968
• DSSTox Substance ID: DTXSID50231448
• Nikkaji Number: J50.740G
• Wikidata: Q83112392
• Mol file: 819-00-1.mol

Synonyms:1,3-Dichloro-1,1-difluoropropane;819-00-1;C3H4Cl2F2;Propane, 1,3-dichloro-1,1-difluoro-;BRN 1734942;HCFC-252fc;SCHEMBL578400;C5H12N3O2P;DTXSID50231448;C5-H12-N3-O2-P;MFCD01320726;AKOS006230398;LS-119958;FT-0676521

Chemical Property of 1,3-Dichloro-1,1-difluoropropane

Chemical Property:

• Vapor Pressure: 81.9mmHg at 25°C
• Refractive Index: 1.3775
• Boiling Point: 84.1°Cat760mmHg
• Flash Point: 1.9°C
• PSA: 0.00000
• Density: 1.332g/cm³
• LogP: 2.44690
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 147.9658118
• Heavy Atom Count: 7
• Complexity: 54.9

Purity/Quality:

98%min ^*data from raw suppliers

1,3-Dichloro-1,1-difluoropropane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 59
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCl)C(F)(F)Cl

Technology Process of 1,3-Dichloro-1,1-difluoropropane

There total 7 articles about 1,3-Dichloro-1,1-difluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1,1,1,3-tetrachloropropane (1070-78-6) → 1,1-difluoro-1,3-dichloropropane (819-00-1) + 1-Fluor-1,1,3-trichlor-propan (818-99-5) + 1,1-Dichloro-1,3-difluoro-propane (121612-64-4)

Guidance literature:

With bromine trifluoride; tin(IV) chloride; In 1,1,2-Trichloro-1,2,2-trifluoroethane; at 20 - 25 ℃;

Reference yield:

1,1,1,3-tetrachloropropane (1070-78-6) → 1,1-difluoro-1,3-dichloropropane (819-00-1) + 1,1,1-trifluoropropylene (677-21-4)

Guidance literature:

With hydrogen fluoride; activated by HF amorphous Zn/chromia catalyst; at 200 ℃;

Reference yield:

1,1,1-trifluoropropylene (677-21-4) → 3-chloro-1,1,1-trifluoropropane (460-35-5) + 1,1-difluoro-1,3-dichloropropane (819-00-1)

Guidance literature:

With hydrogenchloride; aluminium trichloride;

DOI:10.1021/ja00729a021

upstream raw materials:

1-chloro-1,1-difluoro-propane

1,1,1,3-tetrachloropropane

1,1,1-trifluoropropylene

α,α,α-trifluorotoluene

Downstream raw materials:

1,1,1,4-tetrafluoropropane

3-chloro-1,1,1-trifluoropropane

1,1,3-trifluoro-1-chloropropane

Refernces

• 1、 -. "PROCESS". Page/Page column 32. . Retrieved 2009/11/29.
• 2、 -. "PROCESS". Page/Page column 29; 30. . Retrieved 2009/11/29.