677-21-4

Usage

Chemical Properties

Colorless transparent liquefied gas.

Uses

Trifluoropropene is used in the production of fluorosilicone rubber and fluorine-containing silicones used in hydraulic fluids.

Preparation

Trifluoropropene is prepared by fluorination and dehalogenation of 1,1,3,3-tetrachloropropane.

Synthetic route

1,1,1,3-tetrachloropropane (1070-78-6) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With hydrogen fluoride at 225 - 250℃;	90%
With hydrogen fluoride; activated by HF amorphous Zn/chromia catalyst at 200℃; under 760.051 Torr; for 15h; Inert atmosphere;	100 %Chromat.
With hydrogen fluoride; activated by HF amorphous Zn/chromia catalyst at 200℃; under 760.051 Torr; for 15h; Inert atmosphere;	100 %Chromat.

1,1,1-trifluoropropan-2-yl 1,1,2,2,3,3 ,4,4,4-nonafluorobutane-1-sulfonate (118334-94-4) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With potassium fluoride; 18-crown-6 ether In acetylacetone at 100 - 140℃;	80%

3,3,3-Trifluoropropanol (2240-88-2) → 1,1,1,3-tetrafluoropropane (460-36-6) + 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With cesium fluoride; sulphur hexafluoride; 1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene In dichloromethane-d2 at 20℃; for 0.5h; Inert atmosphere; UV-irradiation; Overall yield = 38%;	A 79% B n/a

Vinyl bromide (593-60-2) + metyhyl chlorodifluoroacetate (1514-87-0) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With potassium fluoride; copper(l) iodide In N,N-dimethyl-formamide at 100℃; for 10h;	56%
With potassium fluoride; copper(l) iodide In N,N-dimethyl-formamide at 100 - 120℃; for 7h;

2-bromo-3,3,3-trifluoropropene (1514-82-5) → 1,1-difluoroallene (430-64-8) + 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium In diethyl ether at -78℃; for 0.25h; Stage #2: With methanol In diethyl ether at -78℃;	A 54% B 20%
Stage #1: 2-bromo-3,3,3-trifluoropropene With sec.-butyllithium In diethyl ether; cyclohexane at -105℃; for 0.25h; Stage #2: With methanol In diethyl ether; cyclohexane at -105℃;	A 26 % Spectr. B 60 % Spectr.
Stage #1: 2-bromo-3,3,3-trifluoropropene With n-butyllithium In diethyl ether; cyclohexane at -78℃; for 0.25h; Stage #2: With methanol In diethyl ether; cyclohexane at -78℃;	A 54 % Spectr. B 20 % Spectr.

1,1,1,3,3,3-hexafluoro-2-methyl-propane (382-09-2) → trifluoromethan (75-46-7) + 1,1,1-trifluoropropylene (677-21-4) + 1,1,3,3,3-pentafluoro-2-methyl-1-propene (2253-00-1)

Conditions	Yield
With nickel at 660℃; Product distribution / selectivity;	A 43.5% B 24.5 %Chromat. C 0%

1,1,1-trifluoro-3-iodopropane (460-37-7) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With potassium hydroxide

3-chloro-1,1,1-trifluoropropane (460-35-5) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With dichloromethane; alkali hydroxide
With alkaline solution
durch HCl-Abspaltung;

3-bromo-1,1,1-trifluoropropane (460-32-2) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With potassium hydroxide
With potassium hydroxide

3,3,3-trichloro-1-propene (2233-00-3) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With antimony dichloride trifluoride; antimony(III) fluoride; 1,2-dichloro-ethane

acetic acid-(β,β,β-trifluoro-isopropyl ester) (400-37-3) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
at 490℃;

acrylic acid (79-10-7) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
With sulfur tetrafluoride
With sulfur tetrafluoride at 130℃; for 8h;

chloro-(2,2,2-trifluoro-1-hydroxymethyl-ethyl)-mercury (815-37-2) → 1,1,1-trifluoropropylene (677-21-4)

Conditions	Yield
(pyrolysis);

propionic acid (802294-64-0) + trifluoroacetic acid (76-05-1) → 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,4,4,4-hexafluorobutane (407-59-0) + 1,1,1,4,4,4-hexafluoro-2-(trifluoromethyl)butane (367-53-3) + 1,1,1,6,6,6-hexafluoro-3-trifluoromethyl-hexane (40932-59-0)

Conditions	Yield
With sodium proprionate In water (electrolysis);

1,1,1-trifluoro-3-iodopropane (460-37-7) + perfluorobis(methyl)propylmethyl carbanion (80318-41-8) → 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,2,2,3,3,5,5,5-decafluoro-4-trifluoromethyl-pentane (30320-28-6)

1,1,1-trifluoro-3-iodopropane (460-37-7) → 1,1,1-trifluoropropylene (677-21-4) + perfluoro-2-methyl-2-pentene (359-72-8) + 1,1,1,2,2,3,3,5,5,5-decafluoro-4-trifluoromethyl-pentane (30320-28-6)

Conditions	Yield
With perfluoro-4-methyl-2-pentene; cesium fluoride In N,N-dimethyl-formamide at 60℃; for 18h;

ethene (74-85-1) + iodotrifluoromethane (2314-97-8) → 1,1,1-trifluoro-3-iodopropane (460-37-7) + vinyliodide (593-66-8) + 1,1,1-trifluoropropylene (677-21-4) + acetylene (74-86-2)

Conditions	Yield
under 820 Torr; Quantum yield; Irradiation; CO2 laser induced telomerization;

perfluoro-4-methyl-2-pentene (2070-70-4) → 1,1,1-trifluoropropylene (677-21-4) + perfluoro-2-methyl-2-pentene (359-72-8) + 1,1,1,2,2,3,3,5,5,5-decafluoro-4-trifluoromethyl-pentane (30320-28-6)

Conditions	Yield
With 1,1,1-trifluoro-3-iodopropane; cesium fluoride In N,N-dimethyl-formamide at 60℃; for 18h;

C10H10F3 → 1,1,1-trifluoropropylene (677-21-4) + benzyl radical (2154-56-5)

Conditions	Yield
Rate constant;

ethene (74-85-1) + trifluoroacetic anhydride (407-25-0) → 1,1,1-trifluoropropane (421-07-8) + 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,6,6,6-hexafluorohexane (3834-39-7) + 1,1,1,8,8,8-Hexafluoro-octane (4248-82-2)

Conditions	Yield
at 26.9℃; under 50.3 Torr; Irradiation; Further byproducts given;	A 9.5 % Chromat. B 9.8 % Chromat. C 71.0 % Chromat. D 7.8 % Chromat.
at 26.9℃; under 50.3 Torr; Irradiation; Further byproducts given;	A 8.2 % Chromat. B 8.0 % Chromat. C 83.0 % Chromat. D 0.4 % Chromat.

1,1,1-trifluoro-3-iodopropane (460-37-7) → 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,6,6,6-hexafluorohexane (3834-39-7)

Conditions	Yield
With silver at -73.1 - 76.9℃; Thermodynamic data; activation energy: E(a);

trifluoromethyl radical (2264-21-3) + 3,3,3-trifluoro-propyl (2980-46-3) → 1,1,1-trifluoropropane (421-07-8) + 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,4,4,4-hexafluorobutane (407-59-0) + 1,1,1,6,6,6-hexafluorohexane (3834-39-7)

Conditions	Yield
disproportionation-combination rate constant ratio for gas-phase; comparison of substituent effects;

3,3,3-trifluoro-propyl (2980-46-3) → 1,1,1-trifluoropropane (421-07-8) + 1,1,1-trifluoropropylene (677-21-4) + 1,1,1,4,4,4-hexafluorobutane (407-59-0) + 1,1,1,6,6,6-hexafluorohexane (3834-39-7)

Conditions	Yield
disproportionation-combination rate constant ratio for gas-phase; comparison of substituent effects;

acrylic acid (79-10-7) + sulfur tetrafluoride → 1,1,1-trifluoropropylene (677-21-4)

3,3,3-trichloro-1-propene (2233-00-3) + antimony(III) fluoride (7783-56-4) + 1,2-dichloro-ethane (107-06-2) + antimony dichloride trifluoride → 1,1,1-trifluoropropylene (677-21-4)

1,1,1-trifluoro-3-iodopropane (460-37-7) + ethanolic KOH-solution → 1,1,1-trifluoropropylene (677-21-4)

3-chloro-1,1,1-trifluoropropane (460-35-5) + ethanolic KOH-solution → 1,1,1-trifluoropropylene (677-21-4)

3-chloro-1,1,1-trifluoropropane (460-35-5) + KOH-solution → 1,1,1-trifluoropropylene (677-21-4)

1,1,1-trifluoro-3-iodopropane (460-37-7) + potassium hydroxide → 1,1,1-trifluoropropylene (677-21-4)

ethyl chlorooximidoacetate (95080-93-6) + 1,1,1-trifluoropropylene (677-21-4) → ethyl 5-(trifluoromethyl)-4,5-dihydroisoxazole-3-carboxylate (1432511-65-3)

Conditions	Yield
With sodium hydrogencarbonate In ethyl acetate at -65 - 25℃; for 72h; Inert atmosphere;	100%
With sodium hydrogencarbonate In ethyl acetate at -78 - 20℃; for 60h;	3.2 g

1,1,1-trifluoropropylene (677-21-4) → (rac)-3,3,3-trifluoro-1,2-propanediol (431-39-0)

Conditions	Yield
With pyridine; sodium metabisulfite; osmium(VIII) oxide multistep reaction; stoichiometric and catalytic oxidation of electron-poor olefins with OsO4; other fluoroolefins;	99%
With pyridine; sodium metabisulfite; osmium(VIII) oxide 1) n-hexane, r.t., 1 h, 2) H2O, pyridine, 24 h; Yield given. Multistep reaction;
With pyridine; potassium carbonate; sodium sulfite; potassium hexacyanoferrate(III); K2 1) H2O, t-BuOH, 24 h, 2) 1 h; Yield given. Multistep reaction;

tetrachloromethane (56-23-5) + 1,1,1-trifluoropropylene (677-21-4) → 1,1,1,3-tetrachloro-4,4,4-trifluorobutane (129612-89-1)

Conditions	Yield
With phosphoric acid tributyl ester; iron at 110℃; for 3h;	98.5%
With 2,2'-azobis(isobutyronitrile); 4-fluoroaniline; copper(I) bromide at 60℃; for 4h; Reagent/catalyst; Temperature; Autoclave; Inert atmosphere;	94.2%
iron(III) chloride; phosphoric acid tributyl ester; iron at 80 - 100℃; under 2311.54 Torr;	90%

1,1,1-trifluoropropylene (677-21-4) → 1,3,3,3-tetrafluoro-2-iodo-propane

Conditions	Yield
With antimony; iodine; iodine pentafluoride; sodium iodide at 15℃; under 2250.23 Torr; Temperature; Pressure; Inert atmosphere; Large scale;	98.2%
With iodine monofluoride

1,1,1-trifluoropropylene (677-21-4) + borazine (6569-51-3) → 2-(trifluoropropyl)borazine (155862-04-7)

Conditions	Yield
hydridocarbonyltris(triphenylphosphine)rhodium(I) In neat (no solvent) Kinetics; borazine and the propene (ratio 8.4:1) reacted in the presence of a catalytic amt. Rh-complex at room temp. for 1 h; vacuum line fractionation of mixt. through a 0, -45, -110 and -196°C trap series, product found in the -45°C trap, elem. anal.;	98%

1,1,1-trifluoropropylene (677-21-4) + Methyl thioglycolate (2365-48-2) → methyl 2-(3,3,3-trifluoropropylthio)acetate (1086277-19-1)

Conditions	Yield
2,2’-azobis(4-methoxy-2,4-dimethyl)valeronitrile at -78 - 20℃; for 20h; Product distribution / selectivity;	98%

1,1,1-trifluoropropylene (677-21-4) → 1,2-Dibromo-3,3,3-trifluoropropane (431-21-0)

Conditions	Yield
With bromine at 25℃; for 1.5h; Irradiation;	96%
With bromine Irradiation;	84%
With bromine

Phenylselenyl chloride (5707-04-0) + 1,1,1-trifluoropropylene (677-21-4) → 1-(trifluoromethyl)-2-chloroethyl phenyl selenide (73194-30-6)

Conditions	Yield
In dichloromethane 1) dry ice/acetone, 2) 60 deg C, overnight;	95%

1,1,1-trifluoropropylene (677-21-4) + N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine (93102-05-7) → 1-benzyl-3-(trifluoromethyl)pyrrolidine

Conditions	Yield
With trifluoroacetic acid In dichloromethane at -30 - 20℃; Inert atmosphere;	95%

methanol (67-56-1) + 1,1,1-trifluoropropylene (677-21-4) → 1,1-difluoro-3-methoxy-propene (33119-49-2)

Conditions	Yield
In N,N-dimethyl-formamide at 200℃; under 3750.38 Torr;	93.2%

Triethoxysilane (998-30-1) + 1,1,1-trifluoropropylene (677-21-4) → triethoxy-(3,3,3-trifluoro-propyl)-silane (681-97-0)

Conditions	Yield
With platinum immobilized on polystyrene functionalized with polyethylene glycol and pyridine groups (N/Pt atom ratio of 6:1) at 60℃; under 750.075 Torr; for 6h; Sealed vessel;	92.5%
RhCl(PPh3)3 at 120℃; for 24h;	85%

1,1,1-trifluoropropylene (677-21-4) + carbon monoxide (201230-82-2) → 4,4,4-trifluorobutanal (406-87-1)

Conditions	Yield
Stage #1: carbon monoxide With hydroxo(1,5-cyclooctadiene)rhodium (I) dimer; hydrogen; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In N,N-dimethyl-formamide at 100℃; under 380.026 Torr; for 1h; Stage #2: 1,1,1-trifluoropropylene In N,N-dimethyl-formamide at 100℃; under 190.013 - 570.038 Torr; for 18h;	92%
With dichloro( 1,5-cyclooctadiene)platinum(ll); hydrogen; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; tin(ll) chloride In toluene at 80℃; under 72007.2 Torr; for 48h; Inert atmosphere; Autoclave; Schlenk technique; regioselective reaction;

2,2,2-trifluoroethanol (75-89-8) + 1,1,1-trifluoropropylene (677-21-4) → 1,1-difluoro-3-(2,2,2-trifluoro-ethoxy)-propene (2145-58-6)

Conditions	Yield
With sodium hydroxide In 1-methyl-pyrrolidin-2-one at 60℃; under 1500.15 Torr; Autoclave;	91.8%

ethanol (64-17-5) + 1,1,1-trifluoropropylene (677-21-4) → 3-ethoxy-1,1-difluoro-propene (1993-84-6)

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 170℃; under 5250.53 Torr;	91.2%

1,1,1-trifluoropropylene (677-21-4) → 2-bromo-1,1,1-trifluoropropan-3-ol (311-86-4)

Conditions	Yield
Stage #1: 1,1,1-trifluoropropylene With N-Bromosuccinimide; sulfuric acid; acetic acid at 80 - 100℃; for 4h; Stage #2: In methanol at 40℃; for 9h;	90.2%
With water; hypobromous acid at -10℃;
With mercury(II) diacetate; water; bromine

1,1,1-trifluoropropylene (677-21-4) + tris(trifluoromethyl)phosphine (432-04-2) → 1,1,1-trifluoropropane (421-07-8) + tetrakis(trifluoromethyl)diphosphine (2714-60-5) + bis(trifluoromethyl)-3,3,3-trifluoropropylphosphine

Conditions	Yield
Irradiation;	A 1% B 4% C 90%

1,1,1-trifluoropropylene (677-21-4) + carbon monoxide (201230-82-2) → 4,4,4-trifluorobutanal (406-87-1) + 3,3,3-trifluoro-2-methylpropionaldehyde (58928-28-2)

Conditions	Yield
With hydrogen; carbonylhydridetris(triphenylphosphine)rhodium(I) In toluene at 80℃; for 15h; in an autoclave;	A 2.6% B 90%
Stage #1: carbon monoxide With hydroxo(1,5-cyclooctadiene)rhodium (I) dimer; hydrogen; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In N,N-dimethyl-formamide at 80℃; under 190.013 - 570.038 Torr; for 1h; Stage #2: 1,1,1-trifluoropropylene In N,N-dimethyl-formamide at 80℃; for 15h; Solvent; Reagent/catalyst; Pressure; Temperature;	A 89% B 1.2%
With hydrogen; dicobalt octacarbonyl 1.) toluene, room temperature, 130 atm, 2.) 100 deg C, 20 h; Yield given. Multistep reaction. Yields of byproduct given;

Dichloromethylsilane (75-54-7) + 1,1,1-trifluoropropylene (677-21-4) → (α-trifluoromethylethyl)dichloromethylsilane (84442-91-1)

Conditions	Yield
With bis(benzonitrile)palladium(II) dichloride; triphenylphosphine at 100℃; for 14h;	88%

1,1,1-trifluoropropylene (677-21-4) + (x)C4H8O*C8H11LiSi → 1,1-difluoro-3-(dimethylphenylsilyl)propene (88257-92-5)

Conditions	Yield
In benzene-d6 at 22℃; for 0.25h; Temperature; Solvent; Inert atmosphere; Schlenk technique;	88%

[Ni(1,3-di-tert-butyl-imidazolin-2-ylidene)(CO)2] + 1,1,1-trifluoropropylene (677-21-4) → Ni(CO)(trifluoropropene)(C3H2N2(C(CH3)3)2) + Ni(trifluoropropene)2(C3H2N2(C(CH3)3)2)

Conditions	Yield
In pentane byproducts: CO; (Ar); a soln. of Ni complex treated with ligand, stirred for 30 min; evapd. (vac.), washed (cold pentane); elem. anal.;	A 87% B 0%

1,1,1-trifluoropropylene (677-21-4) + benzenesulfenyl chloride (931-59-9) → 1-(trifluoromethyl)-2-chloroethyl phenyl sulfide (73194-31-7)

Conditions	Yield
In dichloromethane 1) dry ice/acetone, 2) 60 deg C, overnight;	86%
In dichloromethane at 70℃;	86%
In chloroform at 20℃; sealed glass tube;	11.31 g

1,1,1-trifluoropropylene (677-21-4) + o-iodo-methyl-benzoic acid (610-97-9) → dimethyl 2'-[(1E)-3,3,3-trifluoroprop-1-en-1-yl]biphenyl-2,3'-dicarboxylate

Conditions	Yield
Stage #1: o-iodo-methyl-benzoic acid With norbornene; tetrabutylammonium acetate; palladium diacetate; XPhos In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere; Stage #2: 1,1,1-trifluoropropylene In N,N-dimethyl-formamide at 115℃; under 5171.62 Torr; for 2h; Inert atmosphere; Flow reactor;	86%

Dichloromethylsilane (75-54-7) + 1,1,1-trifluoropropylene (677-21-4) → methyl(3,3,3-trifluoropropyl)dichlorosilane (675-62-7)

Conditions	Yield
RhCl(PPh3)3 at 120℃; for 12h;	85%
Irradiation.unter Einwirkung von UV-Licht;
With platinum at 250℃;

1,1,1-trifluoropropylene (677-21-4) + 1,1,1,2,2-pentamethyl-2-phenyldisilane (1130-17-2) → 1,1-difluoro-3-(dimethylphenylsilyl)propene (88257-92-5)

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 6h; Ambient temperature;	85%

1,1,1-trifluoropropylene (677-21-4) + 1,2-diphenyltetramethyldisilane (1145-98-8) → 1,1-difluoro-3-(dimethylphenylsilyl)propene (88257-92-5)

Conditions	Yield
With tetrabutyl ammonium fluoride In N,N,N,N,N,N-hexamethylphosphoric triamide	85%

1,1,1-trifluoropropylene (677-21-4) + tert-butyl 4-phenylbutanoate (16537-11-4) → t-butyl 2-phenylethyl-5,5-difluoro-4-pentenoate

Conditions	Yield
With n-butyllithium; diisopropylamine In tetrahydrofuran at -78℃;	85%

1,1,1-trifluoropropylene (677-21-4) + (2,4-bis(2,6-diisopropylphenylimino)pentan-3-ide-.kappa2N,N')aluminum(I) (325465-25-6) → C32H44AlF3N2

Conditions	Yield
In benzene-d6 at 24.84℃; Glovebox; Schlenk technique; Inert atmosphere;	85%

1,1,1-trifluoropropylene (677-21-4) + C36H51AlN2 → C32H44AlF3N2

Conditions	Yield
In benzene-d6 at 79.84℃; for 5h; Glovebox; Schlenk technique; Inert atmosphere;	85%

1,1,1-trifluoropropylene (677-21-4) + borazine (6569-51-3) → 2-(trifluoropropyl)borazine (155862-04-7) + 2,4-bis-(trifluoropropyl)borazine (155862-05-8) + 2,4,6-tris-(trifluoropropyl)borazine (155862-06-9)

Conditions

Yield

hydridocarbonyltris(triphenylphosphine)rhodium(I) In neat (no solvent) Kinetics; borazine and excess of the propene (ratio 1:2.9) reacted in the presence of a catalytic amt. Rh-complex at room temp. for 16 h, resulting product was a solid with a moist appearance; vacuum line fractionation of mixt. through a -78 and -196°C traps, 2-substd. and 2,4-products found in the -78°C trap; extn. (CH2Cl2) of solid residue, evapn. (ac.), solid sublimed at 80°C (2,4,6-product), elem. anal.;

A 14% B 84% C n/a

Upstream product

• 460-37-7 1,1,1-trifluoro-3-iodopropane 
• 460-32-2 3-bromo-1,1,1-trifluoropropane 
• 400-37-3 acetic acid-(β,β,β-trifluoro-isopropyl ester) 
• 815-37-2 chloro-(2,2,2-trifluoro-1-hydroxymethyl-ethyl)-mercury 
• 802294-64-0 propionic acid 
• 76-05-1 trifluoroacetic acid 
• 593-60-2 Vinyl bromide 
• 1514-87-0 metyhyl chlorodifluoroacetate 
• 80318-41-8 perfluorobis(methyl)propylmethyl carbanion 
• 74-85-1 ethene 
• 2314-97-8 iodotrifluoromethane 
• 2070-70-4 perfluoro-4-methyl-2-pentene 
• 407-25-0 trifluoroacetic anhydride 
• 2264-21-3 trifluoromethyl radical 

Downstream Products

• 675-62-7 methyl(3,3,3-trifluoropropyl)dichlorosilane 
• 1481-41-0 chlorodimethyl-3,3,3-trifluoropropylsilane 
• 453-39-4 1,1,1,4,4,4-hexafluoro-2-iodo-butane 
• 715-18-4 dichloro-phenyl-(3,3,3-trifluoro-propyl)-silane 
• 719-12-0 dichloro-(4-fluoro-phenyl)-(3,3,3-trifluoro-propyl)-silane 
• 421-07-8 1,1,1-trifluoropropane 
• 460-32-2 3-bromo-1,1,1-trifluoropropane 
• 431-21-0 1,2-Dibromo-3,3,3-trifluoropropane 
• 311-86-4 2-bromo-3,3,3-trifluoropropan-1-ol 
• 870-56-4 (3,3,3-trifluoropropyl)dichlorosilane 
• 592-09-6 3,3,3-trifluoropropyltrichlorosilane 
• 665-98-5 dichloro-bis-(3,3,3-trifluoro-propyl)-silane 
• 76-05-1 trifluoroacetic acid 
• 383-68-6 3-acetoxy-2-bromo-1,1,1-trifluoropropane 

Relevant academic research and scientific papers

Versatile Reaction Pathways of 1,1,3,3,3-Pentafluoropropene at Rh(I) Complexes [Rh(E)(PEt3)3] (E=H, GePh3, Si(OEt)3, F, Cl): C-F versus C-H Bond Activation Steps

The reaction of the rhodium(I) complexes [Rh(E)(PEt3)3] (E=GePh3 (1), H (6), F (7)) with 1,1,3,3,3-pentafluoropropene afforded the defluorinative germylation products Z/E-2-(triphenylgermyl)-1,3,3,3-tetrafluoropropene and

COMPOSITIONS AND METHODS FOR AN INTEGRATED 2,3,3,3-TETRAFLUOROPROPENE MANUFACTURING PROCESS

A method of synthesizing 3,3,3-trifluoropropene including contacting 1,3,3,3-tetrachloropropane, in the vapor phase, at a temperature sufficient to effect dehydrochlorination to form 1,1,3-trichloro-1-propene. The 1,1,3-trichloro-1-propene is isolated and subsequently contacted, in the vapor phase, with hydrogen fluoride in the presence of a fluorination catalyst at a temperature sufficient to effect formation of 3,3,3-trifluoropropene.

Activation of pentafluoropropane isomers at a nanoscopic aluminum chlorofluoride: Hydrodefluorination versus dehydrofluorination

The hydrofluorocarbon 245 isomers, 1,1,1,3,3-pentafluoropropane, 1,1,1,2,2- pentafluoropropane, and 1,1,1,2,3-pentafluoro-propane (HFC-245fa, HFC-245cb, and HFC-245eb) were activated through C-F bond activations using aluminium chlorofluoride (ACF) as a catalyst. The addition of the hydrogen source Et3SiH is necessary for the activation of the secondary and tertiary C-F bonds. Multiple C-F bond activations such as hydrodefluorinations and dehydrofluorinations were observed, followed by hydroarylation and Friedel-Crafts-type reactions under mild conditions.

C?H and C?F Bond Activation Reactions of Fluorinated Propenes at Rhodium: Distinctive Reactivity of the Refrigerant HFO-1234yf

The reaction of [Rh(H)(PEt3)3] (1) with the refrigerant HFO-1234yf (2,3,3,3-tetrafluoropropene) affords an efficient route to obtain [Rh(F)(PEt3)3] (3) by C?F bond activation. Catalytic hydrodefluorinations were achieved in the presence of the silane HSiPh3. In the presence of a fluorosilane, 3 provides a C?H bond activation followed by a 1,2-fluorine shift to produce [Rh{(E)-C(CF3)=CHF}(PEt3)3] (4). Similar rearrangements of HFO-1234yf were observed at [Rh(E)(PEt3)3] [E=Bpin (6), C7D7 (8), Me (9)]. The ability to favor C?H bond activation using 3 and fluorosilane is also demonstrated with 3,3,3-trifluoropropene. Studies are supported by DFT calculations.

METHOD FOR PRODUCING 2-CHLORO-3,3,3-TRIFLUOROPROPENE

The invention relates to a method for producing 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) from at least one compound A selected from the group consisting of halopropane of formulae CX3CHClCH2X or CX3CFClCH3, or halopropenes of formula CQX2CCNCH2 and CX2═CClCH2X where X independently represents a fluorine or chlorine atom, characterised in that it comprises bringing said at least one compound A into contact with HF in a gaseous phase in the presence of a fluorination catalyst AlF3 or fluorine-bearing alumina in order to form a gaseous flow B comprising 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) et 3,3,3-trifluoropropene (HFO-1243zf).

PREPARATION OF 2,3,3,3-TETRAFLUOROPROPENE, INTERMEDIATE AND COMPOSITION THEREOF

The present invention provides a process for preparation of 2,3,3,3-tetrafluoropropene, intermediate and composition thereof. Fluoro olefins play an important role as refrigerants. In recent years a fluoro olefin viz. 2,3,3,3-tetrafluoropropene (HFO-1234yf) has attracted attention as a new refrigerant to replace another fluorinated refrigerants.

IMPROVED PROCESS FOR PREPARING 3,3,3-TRIFLUOROPROP-1-ENE

The present application provides a process of preparing 3,3,3-trifluoroprop-1-ene, comprising reacting 3-chloro-1,1,1-trifluoropropane with a base in an aqueous solvent component in the absence of a phase transfer catalyst.

Reactivity of 3,3,3-Trifluoropropyne at Rhodium Complexes: Development of Hydroboration Reactions

The rhodium compounds [Rh(C≡CCF3)(PEt3)3] (2), fac-[RhH(C≡CCF3)2(PEt3)3] (3), and fac-[Rh{(E)-CH=CHCF3}(C≡CCF3)2(PEt3)3] (4) were synthesized by reactions of the rhodium(I) complexes [Rh(H)(PEt3)3] (1) and [Rh(Bpin)(PEt3)3] (5, HBpin=pinacolborane) with the alkyne 3,3,3-trifluoropropyne. Reactivity studies of [Rh(C≡CCF3)(PEt3)3] (2) were performed with CO and 13CO to form [Rh(C≡CCF3)(CO)(PEt3)3] (7) and subsequently trans-[Rh(C≡CCF3)(CO)(PEt3)2] (8) as well as the labeled derivatives. Using 1–4 as catalysts, hydroboration reactions selectively afforded borylated building blocks.

Photochemical activation of SF6 by N-heterocyclic carbenes to provide a deoxyfluorinating reagent

The activation of the greenhouse gas SF6 using electron-rich N-heterocyclic carbenes gave 2,2-difluoroimidazolines or 2,2-difluoroimidazolidines as well as 2-thio derivatives of the carbene precursors. The N-heterocyclic carbenes can also convert SF4 to give similar products. The difluoroimidazolidine derivatives were applied in deoxyfluorination reactions. Furthermore, the activation of SF6 and the fluorination can be coupled in a one-pot process to convert 1-octanol into 1-fluorooctane.

METHOD FOR PRODUCING FLUOROCARBON USING HYDROHALOFLUOROPROPENE

PROBLEM TO BE SOLVED: To provide a method for selectively producing fluorocarbon by efficiently isomerizing a hydrofluoropropene isomer (isomer 1) under the reduction of catalytic performance to produce a corresponding hydrohalofluoropropene isomer (isomer 2) and using the same. SOLUTION: Provided is a method for producing 3,3,3-trifluoropropene by contacting a 1-halogeno-3,3,3-trifluoropropene isomer with a moisture concentration of 100 ppm or lower (isomer 1) in a vapor phase so as to be isomerized to produce a corresponding 1-halogeno-3,3,3-trifluoropropene isomer (isomer 2), and subjecting the 1-halogeno-3,3,3-trifluoropropene isomer (isomer 2) to dehalogenation. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2018,JPOandINPIT