5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Base Information

Chemical Name:5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
CAS No.:1207623-97-9
Molecular Formula:C13H17BN2O3
Molecular Weight:260.09700
Hs Code.:2934999090
Mol file:1207623-97-9.mol

Synonyms:tert-butyl5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-2-carboxyl;TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLINE-2-CARBOXYLATE;tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-isoindole-2-carboxylate;tert-butyl 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydro-isoindole-2-carboxylate;5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one;5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester;7-Aza-2-oxindole-5-boronic acid pinacol ester;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one;

Suppliers and Price of 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one
10mg
$ 45.00

Synthonix
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-azaindolin-2-one 95+%
5g
$ 2160.00

Matrix Scientific
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 97%
5g
$ 4770.00

Matrix Scientific
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 97%
1g
$ 1450.00

Crysdot
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 95+%
1g
$ 703.00

Chemenu
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 97%
1g
$ 499.00

Apolloscientific
5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one
1g
$ 1091.00

American Custom Chemicals Corporation
5-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H,2H,3H-PYRROLO[2,3-B]PYRIDIN-2-ONE 95.00%
5MG
$ 452.28

Ambeed
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 97%
250mg
$ 217.00

Ambeed
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 97%
100mg
$ 145.00

Total 20 raw suppliers

Chemical Property of 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Chemical Property:

Boiling Point:449.5±45.0 °C(Predicted)
PKA:12.81±0.20(Predicted)
PSA：63.94000
Density:1.20±0.1 g/cm3(Predicted)
LogP:0.96050
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

There total 4 articles about 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 183208-34-6
5-bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

: 73183-34-3
bis(pinacol)diborane

: 1207623-97-9
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

Guidance literature:: With potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 120 ℃; for 8h;

Reference yield:

: 183208-32-4
3,3,5-Tribromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

: 1207623-97-9
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; zinc / 5 h / 20 °C

2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 1 h / 110 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; acetic acid; zinc; In 1,4-dioxane;

Reference yield:

: 271-63-6
7-Azaindole

: 1207623-97-9
5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3-dihydropyrrolo[2,3-b]pyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: bromine; tert-butyl alcohol; water / 16 h / 25 °C

2: acetic acid; zinc / 5 h / 20 °C

3: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 1 h / 110 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; water; bromine; potassium acetate; acetic acid; zinc; tert-butyl alcohol; In 1,4-dioxane;