Technology Process of 1H-Indazole-7-methanol, 5-bromo-
There total 4 articles about 1H-Indazole-7-methanol, 5-bromo- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: acetic acid; bromine / 4 h / 0 - 20 °C
2.1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
3.1: potassium acetate; acetic anhydride / chloroform / 1 h / 0 - 20 °C / Inert atmosphere
3.2: 4 h / 60 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C
With
lithium aluminium tetrahydride; bromine; potassium acetate; acetic anhydride; caesium carbonate; acetic acid;
In
tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
2.1: potassium acetate; acetic anhydride / chloroform / 1 h / 0 - 20 °C / Inert atmosphere
2.2: 4 h / 60 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C
With
lithium aluminium tetrahydride; potassium acetate; acetic anhydride; caesium carbonate;
In
tetrahydrofuran; chloroform; N,N-dimethyl-formamide;