3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine

Base Information

Chemical Name:3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
CAS No.:42754-71-2
Molecular Formula:C12H11N5
Molecular Weight:225.253
Hs Code.:
Mol file:42754-71-2.mol

Synonyms:3-benzyl-1(2)H-pyrazolo[3,4-d]pyrimidin-4-ylamine;4-Amino-3-benzyl-pyrazolo[3,4-d]pyrimidin;3-benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine;

Suppliers and Price of 3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine

Chemical Property:

PSA：80.48000
LogP:2.10710

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine

There total 8 articles about 3-benzyl-1H-pyrazolo[3,4-d]pyriMidin-4-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 42754-64-3
5-Amino-3-benzyl-1H-pyrazole-4-carbonitrile

: 42754-71-2
4-Amino-3-benzylpyrazolo<3,4-d>pyrimidine

Guidance literature:: at 200 ℃;

Reference yield:

: 42754-59-6
2-(1-Methoxy-2-phenylethylidene)malononitrile

: 42754-71-2
4-Amino-3-benzylpyrazolo<3,4-d>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / hydrazine hydrochloride; triethylamine / ethanol / 0.25 h / Heating

2: 72 percent / 180 °C

With hydrazine hydrochloride; triethylamine; In ethanol;
DOI:10.1021/ja0264798

Reference yield:

: 103-80-0
phenylacetyl chloride

: 42754-71-2
4-Amino-3-benzylpyrazolo<3,4-d>pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaH / tetrahydrofuran / 0 °C

1.2: 90 percent / tetrahydrofuran / 0 - 20 °C

2.1: 90 percent / aq. NaHCO₃ / dioxane / 2 h / Heating

3.1: 52 percent / hydrazine hydrochloride; triethylamine / ethanol / 0.25 h / Heating

4.1: 72 percent / 180 °C

With hydrazine hydrochloride; sodium hydride; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1021/ja0264798