2-(7-chloro-1H-indol-3-yl)acetonitrile

Base Information

Chemical Name:2-(7-chloro-1H-indol-3-yl)acetonitrile
CAS No.:221377-37-3
Molecular Formula:C10H7ClN2
Molecular Weight:190.62900
Hs Code.:
DSSTox Substance ID:DTXSID50441702
Wikidata:Q82258591
Mol file:221377-37-3.mol

Synonyms:2-(7-chloro-1H-indol-3-yl)acetonitrile;221377-37-3;DTXSID50441702;AKOS006310309;CS-0216025;EN300-321881

Suppliers and Price of 2-(7-chloro-1H-indol-3-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(7-Chloro-1H-indol-3-yl)acetonitrile 95+%
1g
$ 772.00

Chemenu
2-(7-Chloro-1H-indol-3-yl)acetonitrile 95%
1g
$ 729.00

American Custom Chemicals Corporation
7-CHLOROINDOLE-3-ACETONITRILE 95.00%
5MG
$ 503.84

AK Scientific
2-(7-Chloro-1H-indol-3-yl)acetonitrile
5g
$ 4489.00

Total 7 raw suppliers

Chemical Property of 2-(7-chloro-1H-indol-3-yl)acetonitrile

Chemical Property:

PSA：39.58000
LogP:2.88738
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:190.0297759
Heavy Atom Count:13
Complexity:232

Purity/Quality:

99.0%, ^*data from raw suppliers

2-(7-Chloro-1H-indol-3-yl)acetonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)Cl)NC=C2CC#N

Technology Process of 2-(7-chloro-1H-indol-3-yl)acetonitrile

There total 3 articles about 2-(7-chloro-1H-indol-3-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 143-33-9,25596-52-5
sodium cyanide

: 159503-76-1
7-chloro-N,N-dimethyl-1H-indole-3-methanamine

: 221377-37-3
7-chloro-1H-indole-3-acetonitrile

Guidance literature:: With ethyl acetate; In dimethyl sulfoxide; at 80 ℃; for 6h;
DOI:10.1021/jo982277b

Reference yield:

: 53924-05-3
7-chloro-1H-indole

: 221377-37-3
7-chloro-1H-indole-3-acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / CH₂Cl₂ / 2 h / Ambient temperature

2: 82 percent / EtOAc / dimethylsulfoxide / 6 h / 80 °C

With ethyl acetate; In dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jo982277b

Reference yield:

: 773837-37-9
sodium cyanide

: 1008-07-7
7-chloro-1H-indole-3-carboxaldehyde

: 221377-37-3
7-chloro-1H-indole-3-acetonitrile

Guidance literature:: 7-chloro-1H-indole-3-carboxaldehyde; With sodium tetrahydroborate; formamide; In methanol;

sodium cyanide;
DOI:10.3390/molecules26154605