Technology Process of Imidazo[1,2-a]pyridine-6-carboxylic acid, 7-methyl-
There total 5 articles about Imidazo[1,2-a]pyridine-6-carboxylic acid, 7-methyl- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
7-methylimidazo[1,2-a]pyridine-6-carboxylic acid methyl ester;
With
water; sodium hydroxide;
In
methanol;
at 20 - 50 ℃;
for 3h;
With
hydrogenchloride;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ISOPROPYLAMIDE / 24 h / 170 °C / Inert atmosphere
1.2: 0.25 h
2.1: sodium hydroxide / water / 5 h / 100 °C
2.2: Cooling with ice
3.1: sulfuric acid / 85 °C
4.1: sodium hydrogencarbonate / ethanol; water / 1.5 h / 90 °C
5.1: sodium hydroxide; water / methanol / 3 h / 20 - 50 °C
With
sulfuric acid; water; sodium hydrogencarbonate; sodium hydroxide;
In
methanol; ethanol; ISOPROPYLAMIDE; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water / 5 h / 100 °C
1.2: Cooling with ice
2.1: sulfuric acid / 85 °C
3.1: sodium hydrogencarbonate / ethanol; water / 1.5 h / 90 °C
4.1: sodium hydroxide; water / methanol / 3 h / 20 - 50 °C
With
sulfuric acid; water; sodium hydrogencarbonate; sodium hydroxide;
In
methanol; ethanol; water;
