5-Bromo-3-(methylthio)-1H-indazole

Base Information

Chemical Name:5-Bromo-3-(methylthio)-1H-indazole
CAS No.:201227-23-8
Molecular Formula:C8H7BrN2S
Molecular Weight:243.12400
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60705908
Wikidata:Q82639022
Mol file:201227-23-8.mol

Synonyms:5-Bromo-3-(methylthio)-1H-indazole;201227-23-8;5-bromo-3-methylsulfanyl-1H-indazole;5-Bromo-3-(methylsulfanyl)-1H-indazole;SCHEMBL15798958;DTXSID60705908;BGLZAKHTTIEEMC-UHFFFAOYSA-N;BIA22723;MFCD13183072;1h-indazole,5-bromo-3-(methylthio)-;AKOS022174342;DS-6496;CS-0449039;D84309

Suppliers and Price of 5-Bromo-3-(methylthio)-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-bromo-3-(methylthio)-1H-indazole 95%
1g
$ 830.00

Ambeed
5-Bromo-3-(methylthio)-1H-indazole 95%
250mg
$ 282.00

Ambeed
5-Bromo-3-(methylthio)-1H-indazole 95%
100mg
$ 142.00

Abosyn
5-Bromo-3-(methylthio)-1H-indazole 95-98%
1g
$ 2205.00

Total 11 raw suppliers

Chemical Property of 5-Bromo-3-(methylthio)-1H-indazole

Chemical Property:

PSA：53.98000
LogP:3.04730
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:241.95133
Heavy Atom Count:12
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

5-bromo-3-(methylthio)-1H-indazole 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NNC2=C1C=C(C=C2)Br

Technology Process of 5-Bromo-3-(methylthio)-1H-indazole

There total 2 articles about 5-Bromo-3-(methylthio)-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 459133-66-5
5-bromo-3-iodo-1H-indazole

: 5188-07-8
sodium thiomethoxide

: 201227-23-8
5-bromo-3-methylsulfanyl-1H-indazole

Guidance literature:: With copper(l) iodide; In dimethyl sulfoxide; at 120 ℃; for 3h; Inert atmosphere;

Reference yield:

: 53857-57-1
5-bromo-1H-indazole

: 201227-23-8
5-bromo-3-methylsulfanyl-1H-indazole

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; potassium hydroxide / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

2: copper(l) iodide / dimethyl sulfoxide / 3 h / 120 °C / Inert atmosphere

With copper(l) iodide; iodine; potassium hydroxide; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 201227-23-8
5-bromo-3-methylsulfanyl-1H-indazole

: 1613638-92-8
(R)-2-[5-(3-methylsulfanyl-1H-indazol-5-yl)pyridin-3-ylamino]-2-phenylethanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / Inert atmosphere; Reflux

2: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 2 h / 150 °C / Inert atmosphere; Microwave irradiation

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; potassium carbonate; In 1,4-dioxane; water;