(S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate

Base Information

Chemical Name:(S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate
CAS No.:882169-91-7
Molecular Formula:C21H24BrN3O3
Molecular Weight:446.344
Hs Code.:
Mol file:882169-91-7.mol

Synonyms:N-Boc-cis-1,2-cyclohexanediaMine;1-N-Boc-cis-1,2-cyclohexyldiamine;

Suppliers and Price of (S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Chemenu
(S)-tert-butyl(1-((5-bromopyridin-3-yl)oxy)-3-(1H-indol-3-yl)propan-2-yl)carbamate 95%+
100mg
$ 1816.00

Chemenu
(S)-tert-butyl(1-((5-bromopyridin-3-yl)oxy)-3-(1H-indol-3-yl)propan-2-yl)carbamate 95%+
250mg
$ 1404.00

Total 9 raw suppliers

Chemical Property of (S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate

Chemical Property:

PSA：79.73000
LogP:5.04460

Purity/Quality:

NLT 98% ^*data from raw suppliers

(S)-tert-butyl(1-((5-bromopyridin-3-yl)oxy)-3-(1H-indol-3-yl)propan-2-yl)carbamate 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate

There total 1 articles about (S)-tert-butyl 1-(5-bromopyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.7%

: 74115-13-2
5-bromopyridine-3-ol

: 110659-38-6,143259-51-2,82689-19-8
N-t-butoxycarbonyl-tryptophanol

: 882169-91-7
(S)-[2-(5-bromopyridin-3-yloxy)-1-(1H-indol-3-ylmethyl)ethyl]carbamic acid tert-butyl ester

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; at 0 - 20 ℃;

Reference yield: 88.0%

: 882169-91-7
(S)-[2-(5-bromopyridin-3-yloxy)-1-(1H-indol-3-ylmethyl)ethyl]carbamic acid tert-butyl ester

: 126747-14-6
4-cyanophenylboronic acid

: 552330-73-1
tert-butyl (1S)-2-{[5-(4-cyanophenyl)pyridin-3-yl]oxy}-1-(1H-indol-3-ylmethyl)ethylcarbamate

Guidance literature:: (S)-[2-(5-bromopyridin-3-yloxy)-1-(1H-indol-3-ylmethyl)ethyl]carbamic acid tert-butyl ester; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 20 ℃; for 0.5h;

4-cyanophenylboronic acid; In 1,2-dimethoxyethane; ethanol; at 20 ℃; for 0.25h;

With sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; for 4h; Heating / reflux;