6-Bromo-8-fluoronaphthalen-2-ol

Base Information

Chemical Name:6-Bromo-8-fluoronaphthalen-2-ol
CAS No.:82995-06-0
Molecular Formula:C10H6BrFO
Molecular Weight:241.059
Hs Code.:2908199090
DSSTox Substance ID:DTXSID00459857
Wikidata:Q82283728
Mol file:82995-06-0.mol

Synonyms:6-Bromo-8-fluoronaphthalen-2-ol;82995-06-0;6-bromo-8-fluoro-2-naphthol;6-bromo-8-fluoro-naphthalen-2-ol;SCHEMBL5980541;DTXSID00459857;NDCOKFWKXFDSKD-UHFFFAOYSA-N;MFCD09037977;AKOS015994830;BS-48605;CS-0199475;J-518415

Suppliers and Price of 6-Bromo-8-fluoronaphthalen-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6-Bromo-8-fluoronaphthalen-2-ol 95+%
250mg
$ 1286.00

Crysdot
6-Bromo-8-fluoronaphthalen-2-ol 95+%
5g
$ 1632.00

Crysdot
6-Bromo-8-fluoronaphthalen-2-ol 95+%
1g
$ 465.00

Chemenu
6-Bromo-8-fluoronaphthalen-2-ol 95%
1g
$ 439.00

Chemenu
6-Bromo-8-fluoronaphthalen-2-ol 95%
5g
$ 1539.00

American Custom Chemicals Corporation
6-BROMO-8-FLUORONAPHTHALEN-2-OL 95.00%
5MG
$ 499.38

AK Scientific
6-Bromo-8-fluoronaphthalen-2-ol
1g
$ 1237.00

Total 15 raw suppliers

Chemical Property of 6-Bromo-8-fluoronaphthalen-2-ol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:352.266°C at 760 mmHg
Flash Point:166.845°C
PSA：20.23000
Density:1.693g/cm³
LogP:3.44700
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:239.95861
Heavy Atom Count:13
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-8-fluoronaphthalen-2-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC2=C(C=C(C=C21)Br)F)O

Technology Process of 6-Bromo-8-fluoronaphthalen-2-ol

There total 10 articles about 6-Bromo-8-fluoronaphthalen-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 550998-28-2
1,6-dibromo-8-fluoro-2-naphthol

: 82995-06-0
3-bromo-1-fluoro-7-hydroxynaphthalene

Guidance literature:: With hydrogenchloride; acetic acid; tin(ll) chloride; at 100 ℃; for 1h;
DOI:10.1021/jm058173s

Reference yield:

: 13791-03-2
1-fluoro-7-methoxynaphthalene

: 82995-06-0
3-bromo-1-fluoro-7-hydroxynaphthalene

Guidance literature:: Multi-step reaction with 3 steps

1: 3.99 g / BBr₃ / CH₂Cl₂ / 0 - 20 °C

2: 62 percent / Br₂; acetic acid / 1 h / 100 °C

3: 41 percent / SnCl₂; aq. HCl; acetic acid / 1 h / 100 °C

With hydrogenchloride; bromine; boron tribromide; acetic acid; tin(ll) chloride; In dichloromethane;
DOI:10.1021/jm058173s

Reference yield:

: 118-46-7
8-amino-2-naphthol

: 82995-06-0
3-bromo-1-fluoro-7-hydroxynaphthalene

Guidance literature:: Multi-step reaction with 7 steps

1.1: methanol / 1.5 h / Heating

2.1: K₂CO₃ / acetone / 6 h / Heating

3.1: aq. HCl / 5 h / Heating

4.1: aq. HCl; NaNO₂ / 0.5 h / 10 °C

4.2: aq. HBF₄

4.3: xylene / 1 h / Heating

5.1: 3.99 g / BBr₃ / CH₂Cl₂ / 0 - 20 °C

6.1: 62 percent / Br₂; acetic acid / 1 h / 100 °C

7.1: 41 percent / SnCl₂; aq. HCl; acetic acid / 1 h / 100 °C

With hydrogenchloride; bromine; boron tribromide; potassium carbonate; acetic acid; tin(ll) chloride; sodium nitrite; In methanol; dichloromethane; acetone;
DOI:10.1021/jm058173s