4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER

Base Information

Chemical Name:4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER
CAS No.:701232-18-0
Molecular Formula:C20H27BrO3
Molecular Weight:395.337
Hs Code.:
Mol file:701232-18-0.mol

Synonyms:Ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)-phenyl)cyclohexyl)acetate;4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER;Cyclohexaneacetic acid, 4-[4-(2-broMo-2-Methyl-1-oxopropyl)phenyl]-, ethyl ester

Suppliers and Price of 4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)-phenyl)cyclohexyl)acetate 95+%
1g
$ 1647.00

Matrix Scientific
Ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)-phenyl)cyclohexyl)acetate 95+%
250mg
$ 742.00

ChemScene
Cyclohexaneaceticacid,4-[4-(2-bromo-2-methyl-1-oxopropyl)phenyl]-,ethylester
500mg
$ 495.00

AK Scientific
Ethyl2-(4-(4-(2-bromo-2-methylpropanoyl)-phenyl)cyclohexyl)acetate
250mg
$ 1051.00

Total 7 raw suppliers

Chemical Property of 4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER

Chemical Property:

Vapor Pressure:1.18E-08mmHg at 25°C
Boiling Point:460.3°C at 760 mmHg
Flash Point:232.2°C
PSA：43.37000
Density:1.225g/cm³
LogP:5.26980

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)-phenyl)cyclohexyl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER

There total 3 articles about 4-[4-(2-BROMO-2-METHYL-1-OXOPROPYL)PHENYL]-CYCLOHEXANEACETIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20769-85-1
2-bromoisobutyric acid bromide

: 411238-92-1
ethyl 2-(4-phenylcyclohexyl)acetate

: 701232-18-0
ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)phenyl)cyclohexyl)acetate

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 0 ℃;

Reference yield:

: 115880-04-1
ethyl 2-(4-phenylcyclohexylidene)acetate

: 701232-18-0
ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)phenyl)cyclohexyl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 1 h / 20 °C

2: aluminum (III) chloride / dichloromethane / 1 h / 0 °C

With aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; In ethanol; dichloromethane;
DOI:10.1021/jm500135c

Reference yield:

: 4894-75-1
1-phenyl-4-cyclohexanone

: 701232-18-0
ethyl 2-(4-(4-(2-bromo-2-methylpropanoyl)phenyl)cyclohexyl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C

1.2: 0.5 h

2.1: palladium 10% on activated carbon; hydrogen / ethanol / 1 h / 20 °C

3.1: aluminum (III) chloride / dichloromethane / 1 h / 0 °C

With aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; sodium hydride; In ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm500135c