5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid

Base Information

Chemical Name:5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid
CAS No.:91569-59-4
Molecular Formula:C12H11NO3
Molecular Weight:217.22
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70424330
Wikidata:Q82236859
Mol file:91569-59-4.mol

Synonyms:91569-59-4;5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid;5-methyl-3-(4-methylphenyl)-1,2-oxazole-4-carboxylic acid;5-METHYL-3-(P-TOLYL)ISOXAZOLE-4-CARBOXYLIC ACID;5-methyl-3-p-tolylisoxazole-4-carboxylic acid;5-methyl-3-(4-methylphenyl)isoxazole-4-carboxylic acid;4-Isoxazolecarboxylic acid, 5-methyl-3-(4-methylphenyl)-;SCHEMBL3862966;DTXSID70424330;MFCD07376089;AKOS000300382;BB 0253715;CS-0243521;A19309;EN300-264780;5-METHYL-3-(P-TOLYL)ISOXAZOLE-4-CARBOXYLICACID;F1907-0515

Suppliers and Price of 5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid
555mg
$ 194.00

Matrix Scientific
5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid
1g
$ 298.00

Crysdot
5-Methyl-3-(p-tolyl)isoxazole-4-carboxylicacid 97%
5g
$ 874.00

American Custom Chemicals Corporation
5-METHYL-3-PARA-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID 95.00%
1G
$ 750.75

American Custom Chemicals Corporation
5-METHYL-3-PARA-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID 95.00%
0.5G
$ 682.00

AK Scientific
5-Methyl-3-p-tolyl-isoxazole-4-carboxylicacid
100mg
$ 216.00

AK Scientific
5-Methyl-3-p-tolyl-isoxazole-4-carboxylicacid
500mg
$ 351.00

Total 8 raw suppliers

Chemical Property of 5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid

Chemical Property:

PSA：63.33000
LogP:2.65660
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:261

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NOC(=C2C(=O)O)C

Technology Process of 5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid

There total 2 articles about 5-Methyl-3-p-tolyl-isoxazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36288-37-6
N-hydroxy-4-methylbenzenecarboximidoyl chloride

: 91569-59-4
3-(4-tolyl)-5-methylisoxazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (i) Na, MeOH, (ii) /BRN= 506727/

2: aq. KOH / ethanol

With potassium hydroxide; In ethanol;
DOI:10.1039/jr9630005838

Reference yield:

: 79379-87-6
methyl 5-methyl-3-(p-tolyl)isoxazole-4-carboxylate

: 91569-59-4
3-(4-tolyl)-5-methylisoxazole-4-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol;
DOI:10.1039/jr9630005838

Reference yield:

: C₃H₅N₂O₂PolS

: 91569-59-4
3-(4-tolyl)-5-methylisoxazole-4-carboxylic acid

: C₁₅H₁₄N₃O₄PolS

Guidance literature:: With N-ethyl-N,N-diisopropylamine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V); In 1-methyl-pyrrolidin-2-one; at 25 ℃; for 24h; Wang resin
DOI:10.1021/jm300931y