4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine

Base Information Edit

Chemical Name:4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine
CAS No.:68559-60-4
Molecular Formula:C7H7NOS
Molecular Weight:153.20158
Hs Code.:2934990002
European Community (EC) Number:641-907-7
UNII:J3532AWK7T
Wikidata:Q27281111
Mol file:68559-60-4.mol

Synonyms:68559-60-4;6,7-Dihydrothieno[3,2-c]pyridin-4(5H)-one;4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine;6.7-dihydrothieno[3.2.c]pyridin-4(5H)-one;4H,5H,6H,7H-thieno[3,2-c]pyridin-4-one;6,7-dihydro-5H-thieno[3,2-c]pyridin-4-one;J3532AWK7T;4-Oxo-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine;Thieno(3,2-C)pyridin-4(5H)-one, 6,7-dihydro-;6,7-Dihydrothieno[3,2-c]-pyridin-4(5H)-one;UNII-J3532AWK7T;Ticlopidine hydrochloride impurity B [EP];6,7-dihydrothieno[3,2-c]pyridine-4(5H)-one;SCHEMBL4303248;SFNZVNVCJWVPDM-UHFFFAOYSA-N;MFCD22372780;AKOS023410661;SB17523;AS-44114;DB-333298;CS-0132514;EN300-205477;5H,6H,7H-THIENO[3,2-C]PYRIDIN-4-ONE;4-Oxo-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine;Q27281111;Z1486036948;TICLOPIDINE HYDROCHLORIDE IMPURITY B [EP IMPURITY];Ticlodipine EP Impurity B/ Ticlodipine Related Compound A (ClopidogrelAmide Impurity)

Suppliers and Price of 4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Oxo-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
50mg
$ 1260.00

Medical Isotopes, Inc.
4-Oxo-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
50 mg
$ 2200.00

Atlantic Research Chemicals
4H,5H,6H,7H-Thieno[3,2-c]pyridin-4-one 95%
1gm:
$ 378.20

Alichem
6,7-Dihydrothieno[3,2-c]pyridin-4(5H)-one
25g
$ 3939.60

Alichem
6,7-Dihydrothieno[3,2-c]pyridin-4(5H)-one
5g
$ 1672.32

Total 12 raw suppliers

Chemical Property of 4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine Edit

Chemical Property:

Boiling Point:417.1±34.0 °C(Predicted)
PKA:14.35±0.20(Predicted)
PSA：60.83000
Density:1.295±0.06 g/cm3(Predicted)
LogP:1.04440
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:153.02483502
Heavy Atom Count:10
Complexity:160

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

4-Oxo-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC(=O)C2=C1SC=C2
Uses 4-Oxo-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine is an impurity in the preparation of Ticlopidine Hydrochloride (T438325), an antithrombotic. A platelet aggregation inhibitor.

Technology Process of 4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine

There total 11 articles about 4-Oxo-4,5,6,7-tetrahydrothieno-(3,2-C)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 30433-91-1
[2-(2-thyenyl)ethyl]amine

: 32315-10-9
bis(trichloromethyl) carbonate

: 68559-60-4
6,7-dihydrothieno[3,2-c]pyridine-4(5H)-one

Guidance literature:: [2-(2-thyenyl)ethyl]amine; bis(trichloromethyl) carbonate; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

With iron(III) chloride; In dichloromethane; at 50 ℃; for 2h; Inert atmosphere;

Reference yield: 71.0%

: 30433-91-1
[2-(2-thyenyl)ethyl]amine

: 75-44-5
phosgene

: 68559-60-4
6,7-dihydrothieno[3,2-c]pyridine-4(5H)-one

Guidance literature:: [2-(2-thyenyl)ethyl]amine; phosgene; With sodium hydrogencarbonate; In dichloromethane; water; at 0 ℃; for 5h;

With iron(III) chloride; In dichloromethane; water; at 50 ℃; for 0.666667h;