5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl-

Base Information

Chemical Name:5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl-
CAS No.:297142-51-9
Molecular Formula:C11H8FNO2
Molecular Weight:205.19
Hs Code.:
Mol file:297142-51-9.mol

Synonyms:5(4H)-OXAZOLONE, 4-[(2-FLUOROPHENYL)METHYLENE]-2-METHYL-;4-[(2-FLUOROPHENYL)METHYLENE]-2-METHYL-5(4H)-OXAZOLONE;

Suppliers and Price of 5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl-

Chemical Property:

Boiling Point:291.3±50.0 °C(Predicted)
PKA:0.71±0.20(Predicted)
PSA：38.66000
Density:1.25±0.1 g/cm3(Predicted)
LogP:1.57740

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl-

There total 1 articles about 5(4H)-Oxazolone, 4-[(2-fluorophenyl)Methylene]-2-Methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 446-52-6
2-Fluorobenzaldehyde

: 543-24-8
N-acetylglycine

: 297142-51-9
4-(2-fluorophenyl)methylene-2-methyl-5(4H)-oxazolone

Guidance literature:: With sodium acetate; acetic anhydride; at 40 - 135 ℃; for 3.75h;
DOI:10.1080/00397911.2012.748075

Reference yield: 69.0%

: 297142-51-9
4-(2-fluorophenyl)methylene-2-methyl-5(4H)-oxazolone

: 99-92-3
p-aminobenzophenone

: 1394856-42-8
1-(4-acetylphenyl)-4-(2-fluorobenzylidene)-2-methyl-1H-imidazol-5(4H)-one

Guidance literature:: With sodium acetate; acetic acid; Microwave irradiation; Inert atmosphere;
DOI:10.1007/s00044-012-0190-z

Reference yield:

: 297142-51-9
4-(2-fluorophenyl)methylene-2-methyl-5(4H)-oxazolone

: 151073-66-4
methyl (S)-2-acetamido-3-(2-fluorophenyl)propanoate

: 151073-66-4
(R)-methyl 2-acetoamido-3-(o-fluorophenyl)propionate

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 5 h / 20 °C

2: 1.1C₅₈H₃₄O₁₀^(4-)*4OZr⁽²⁺⁾*4H₂O*2Zr⁽⁴⁺⁾*4HO^(1-)*0.8C₈H₁₂ClIr*0.9C₆₀H₃₈NO₁₀P^(4-); hydrogen / dichloromethane / 20 h / 25 °C / 3750.38 Torr

With hydrogen; 1.1C₅₈H₃₄O₁₀^(4-)*4OZr⁽²⁺⁾*4H₂O*2Zr⁽⁴⁺⁾*4HO^(1-)*0.8C₈H₁₂ClIr*0.9C₆₀H₃₈NO₁₀P^(4-); In methanol; dichloromethane;
DOI:10.1021/jacs.0c00637