1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe

Base Information

• Chemical Name: 1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe
• CAS No.: 1092464-43-1
• Molecular Formula: C12H13F3N2O3S
• Molecular Weight: 322.308
• Mol file: 1092464-43-1.mol

Synonyms:1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe

Chemical Property of 1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe

Chemical Property:

• PSA: 78.35000
• LogP: 3.33880

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe

There total 1 articles about 1-(3-(trifluoroMethyl)phenylsulfonyl)piperidin-4-one oxiMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one (216983-38-9) → 1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one oxime (1092464-43-1)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; at 20 ℃; for 3h;

Reference yield: 71.0%

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one oxime (1092464-43-1) + 4-fluoro-N-methylaniline (459-59-6) + trichloromethyl chloroformate (503-38-8) → 1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one O-(4-fluorophenyl)(methyl)carbamoyl oxime (1092464-10-2)

Guidance literature:

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one oxime; trichloromethyl chloroformate; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

4-fluoro-N-methylaniline; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield: 45.0%

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one oxime (1092464-43-1) + para-fluorophenyl isocyanate (1195-45-5) → 1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one O-4-fluorophenylcarbamoyl oxime (1092464-03-3)

Guidance literature:

With pyridine; In ethanol; at 20 ℃; for 17h;

upstream raw materials:

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one

Downstream raw materials:

C₁₂H₁₅F₃N₂O₂S

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one O-(4-fluorophenyl)(methyl)carbamoyl oxime

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one O-propylcarbamoyl oxime

1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-4-one O-4-fluorophenylcarbamoyl oxime