4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid

Base Information

Chemical Name:4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid
CAS No.:169032-03-5
Molecular Formula:C10H10O3
Molecular Weight:178.1894
Hs Code.:2918199090
DSSTox Substance ID:DTXSID30440298
Mol file:169032-03-5.mol

Synonyms:4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid;169032-03-5;4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid;DTXSID30440298;AKOS015924833;CS-W007016;AS-68692;A882124;1H-Indene-2-carboxylic acid, 2,3-dihydro-4-hydroxy-

Suppliers and Price of 4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid 95+%
1g
$ 1485.00

Chemenu
4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid 95%
1g
$ 1403.00

American Custom Chemicals Corporation
4-HYDROXY-2,3-DIHYDRO-1H-INDENE-2-CARBOXYLIC ACID 95.00%
5MG
$ 498.75

Alichem
4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid
1g
$ 1635.00

Alichem
4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid
25mg
$ 199.28

AK Scientific
4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid
100mg
$ 383.00

Total 13 raw suppliers

Chemical Property of 4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid

Chemical Property:

Boiling Point:390.3±42.0 °C(Predicted)
PKA:4.45±0.20(Predicted)
PSA：57.53000
Density:1.379±0.06 g/cm3(Predicted)
LogP:1.19160
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.062994177
Heavy Atom Count:13
Complexity:214

Purity/Quality:

99%, ^*data from raw suppliers

4-Hydroxy-2,3-dihydro-1H-indene-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC2=C1C=CC=C2O)C(=O)O

Technology Process of 4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid

There total 4 articles about 4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 163456-61-9
methyl 4-methoxyindan-2-carboxylate

: 169032-03-5
4-hydroxyindan-2-carboxylic acid

Guidance literature:: With hydrogen bromide; acetic acid; for 4h; Heating;
DOI:10.1248/cpb.42.1756

Reference yield:

: 13336-31-7
4-methoxylindanone

: 169032-03-5
4-hydroxyindan-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / NaH / tetrahydrofuran / 6 h / Heating

2: 98 percent / H₂, concd. HCl / 10percent Pd-C / methanol / 12 h / 3040 Torr

3: 100 percent / 48percent HBr, AcOH / 4 h / Heating

With hydrogenchloride; hydrogen bromide; hydrogen; sodium hydride; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.42.1756

Reference yield:

: 40731-98-4
4-hydroxy-2,3-dihydroindan-1-one

: 169032-03-5
4-hydroxyindan-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / K₂CO₃ / acetone / 8 h / Heating

2: 100 percent / NaH / tetrahydrofuran / 6 h / Heating

3: 98 percent / H₂, concd. HCl / 10percent Pd-C / methanol / 12 h / 3040 Torr

4: 100 percent / 48percent HBr, AcOH / 4 h / Heating

With hydrogenchloride; hydrogen bromide; hydrogen; sodium hydride; potassium carbonate; acetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; acetone;
DOI:10.1248/cpb.42.1756