Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate

Base Information

Chemical Name:Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate
CAS No.:163456-61-9
Molecular Formula:C₁₂H₁₄O₃
Molecular Weight:206.241
Hs Code.:2918990090
DSSTox Substance ID:DTXSID10437500
Mol file:163456-61-9.mol

Synonyms:163456-61-9;Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate;4-METHOXY-INDAN-2-CARBOXYLIC ACID METHYL ESTER;Methyl 4-methoxyindan-2-carboxylate;1H-Indene-2-carboxylic acid, 2,3-dihydro-4-methoxy-, methyl ester;Methyl4-methoxy-2,3-dihydro-1H-indene-2-carboxylate;DTXSID10437500;4-Methoxy-indan-2-carboxylicacidmethylester;4-methoxyindan-2-carboxylic acid methyl ester;A852998

Suppliers and Price of Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-methoxy-2,3-dihydro-1H-indene-2-carboxylate 95+%
1g
$ 535.00

American Custom Chemicals Corporation
4-METHOXY-INDAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 501.30

Total 6 raw suppliers

Chemical Property of Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate

Chemical Property:

Boiling Point:311.0±42.0 °C(Predicted)
PSA：35.53000
Density:1.144±0.06 g/cm3(Predicted)
LogP:1.58300
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:206.094294304
Heavy Atom Count:15
Complexity:239

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-methoxy-2,3-dihydro-1H-indene-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1CC(C2)C(=O)OC

Technology Process of Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate

There total 3 articles about Methyl 4-methoxy-2,3-dihydro-1H-indene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 131308-27-5
methyl 4-methoxy-2,3-dihydro-1-oxo-1H-indene-2-carboxylate

: 163456-61-9
methyl 4-methoxyindan-2-carboxylate

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 12h; under 3040 Torr;
DOI:10.1248/cpb.42.1756

Reference yield:

: 13336-31-7
4-methoxylindanone

: 163456-61-9
methyl 4-methoxyindan-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / NaH / tetrahydrofuran / 6 h / Heating

2: 98 percent / H₂, concd. HCl / 10percent Pd-C / methanol / 12 h / 3040 Torr

With hydrogenchloride; hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1248/cpb.42.1756

Reference yield:

: 40731-98-4
4-hydroxy-2,3-dihydroindan-1-one

: 163456-61-9
methyl 4-methoxyindan-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / K₂CO₃ / acetone / 8 h / Heating

2: 100 percent / NaH / tetrahydrofuran / 6 h / Heating

3: 98 percent / H₂, concd. HCl / 10percent Pd-C / methanol / 12 h / 3040 Torr

With hydrogenchloride; hydrogen; sodium hydride; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; methanol; acetone;
DOI:10.1248/cpb.42.1756