3-Fluoro-5-hydroxybenzonitrile

Base Information

• Chemical Name: 3-Fluoro-5-hydroxybenzonitrile
• CAS No.: 473923-95-4
• Molecular Formula: C7H4FNO
• Molecular Weight: 137.113
• Hs Code.: 2926909090
• Mol file: 473923-95-4.mol

Synonyms:3-Fluoro-5-hydroxybenzonitrile;3-Cyano-5-fluorophenol

Chemical Property of 3-Fluoro-5-hydroxybenzonitrile

Chemical Property:

• Boiling Point: 255.8±25.0 °C(Predicted)
• PKA: 7.58±0.10(Predicted)
• PSA: 44.02000
• Density: 1.34±0.1 g/cm3(Predicted)
• LogP: 1.40298
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoro-5-hydroxybenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 22-41-51/53
• Safety Statements: 26-39-61

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Fluoro-5-hydroxybenzonitrile

There total 2 articles about 3-Fluoro-5-hydroxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-fluoro-5-hydroxy-benzonitrile (473923-95-4)

Guidance literature:

Reference yield:

→ 3-fluoro-5-hydroxy-benzonitrile (473923-95-4) + 3-Fluoro-5-methoxybenzonitrile (439280-18-9)

Guidance literature:

Reference yield: 100.0%

3-fluoro-5-hydroxy-benzonitrile (473923-95-4) + methyl 2-bromo-3-fluoro-6-(methylsulfonyl)benzoate → methyl 2-bromo-3-(3-cyano-5-fluorophenoxy)-6-(methylsulfonyl)benzoate

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 90 ℃; for 16h;

Downstream raw materials:

C₂₄H₂₇FN₄O₃

C₁₇H₁₂F₂N₂O₅

C₁₄H₁₄FNO₃

3-fluoro-5-hydroxybenzaldehyde