Ritropirronium bromide

Base Information Edit

Chemical Name:Ritropirronium bromide
CAS No.:53808-86-9
Deprecated CAS:53808-86-9
Molecular Formula:Br*C₁₉H₂₈NO₃
Molecular Weight:398.34
Hs Code.:
UNII:9SFK0PX55W,W76196A5NR
NCI Thesaurus Code:C90701
Mol file:53808-86-9.mol

Synonyms:Ritropirronium bromide;475468-09-8;58493-54-2;(R,R)-Glycopyrrolate;Glycopyrrolate, threo-;(2R,3'R)-Glycopyrrolate Bromide;9SFK0PX55W;Glycopyrrolate, (2R,3R)-;Glycopyrronium bromide, threo-;W76196A5NR;Glycopyrrolate, (R-(R*,R*))-;Glycopyrronium bromide, (2R,3R)-;threo-Glycopyrronium bromide;[(3R)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2R)-2-cyclopentyl-2-hydroxy-2-phenylacetate;bromide;(3R)-3-(((2R)-2-Cyclopentyl-2-hydroxy-2-phenylacetyl)oxy)-1,1-dimethylpyrrolidinium bromide (1:1);Pyrrolidinium, 3-(((2R)-cyclopentylhydroxyphenylacetyl)oxy)-1,1-dimethyl-, bromide, (3R)-;Pyrrolidinium, 3-((cyclopentylhydroxyphenylacetyl)oxy)-1,1-dimethyl-, bromide, (R*,R*)-;rel-(R)-3-((R)-2-Cyclopentyl-2-hydroxy-2-phenylacetoxy)-1,1-dimethylpyrrolidin-1-ium bromide;Pyrrolidinium, 3-(((2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy)-1,1-dimethyl-, bromide (1:1), (3R)-;Pyrrolidinium, 3-(((2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy)-1,1-dimethyl-, bromide (1:1), (3R)-rel-;Pyrrolidinium, 3-[[(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy]-1,1-dimethyl-, bromide (1:1), (3R)-;UNII-9SFK0PX55W;GLYCOPYRROLATE, D-;SCHEMBL131054;UNII-W76196A5NR;HY-B0761;GLYCOPYRROLATE, (2R,3'R)-;AKOS040736327;CS-0009647;erythro-3-Hydroxy-1,1-dimethylpyrrolidinium bromide alpha-cyclopentylmandelate;erythro-3-Hydroxy-1,1-dimethylpyrrolidinium bromide alpha-cyclopentylmandelate.;(3RS)-3-[(2RS)-(2-Cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidinium Bromide

Suppliers and Price of Ritropirronium bromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ritropirronium bromide Edit

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：46.53000
Density:g/cm³
LogP:-0.58090
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:397.12526
Heavy Atom Count:24
Complexity:424

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[N+]1(CCC(C1)OC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.[Br-]
Isomeric SMILES:C[N+]1(CC[C@H](C1)OC(=O)[C@@](C2CCCC2)(C3=CC=CC=C3)O)C.[Br-]
Recent EU Clinical Trials:A single blind study comparing the efficacy of Glycopyrronium and Hyoscine on drooling in children with neurodisability - DRI Trial (Drooling Reduction Intervention)

Technology Process of Ritropirronium bromide

There total 32 articles about Ritropirronium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: C₁₇H₂₂Br₂O₃

: 124-40-3
dimethyl amine

: 596-51-0,129784-12-9,201667-20-1,53808-86-9,58493-54-2
glycopyrronium bromide

Guidance literature:: With potassium carbonate; In methanol; at 65 ℃;

Reference yield: 63.0%

: 74-83-9
methyl bromide

: 1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate 5-nitroisophthalic acid

: 596-51-0,129784-12-9,201667-20-1,53808-86-9,58493-54-2
(3RS)-3-[(2SR)-(2-cyclopentyl-2-hydroxy-2-phenyl-acetyl)oxy]-1,1-dimethylpyrrolidinium bromide

Guidance literature:: 1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate 5-nitroisophthalic acid; With potassium carbonate; In Isopropyl acetate; water; for 0.25h; Industrial scale;

methyl bromide; In ethyl acetate; at 0 - 20 ℃; for 5h; Industrial scale;