D-Cyclobutylalanine

Base Information

• Chemical Name: D-Cyclobutylalanine
• CAS No.: 174266-00-3
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.18362
• Hs Code.: 2922498590
• Mol file: 174266-00-3.mol

Synonyms:D-Cyclobutylalanine;

Chemical Property of D-Cyclobutylalanine

Chemical Property:

• PSA: 63.32000
• LogP: 1.28880
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Amino-3-cyclobutylpropanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-Cyclobutylalanine

There total 9 articles about D-Cyclobutylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-2-(tert-butoxycarbonylamino)-3-cyclobutylpropanoate diisopropylamine salt → 3-cyclobutyl-D-alanine (1201593-65-8,174266-00-3)

Guidance literature:

With sulfuric acid; In dichloromethane;

Reference yield:

methoxycarbonyl-3-cyclobutyl-D-alanine + methyloxirane (75-56-9,16033-71-9) → 3-cyclobutyl-D-alanine (1201593-65-8,174266-00-3)

Guidance literature:

With hydrogenchloride; In ethanol; water;

Reference yield:

C9H15NO3 → (S)-2-amino-3-cyclobutylpropanoic acid (1201593-65-8,174266-00-3)

Guidance literature:

With L-acylase; sodium hydroxide; In water; at 37 ℃; for 40h; pH=7.5; Enzymatic reaction;

DOI:10.1021/acs.jmedchem.8b01201

upstream raw materials:

(Bromomethyl)cyclobutane

2-acetylaminomalonic acid diethyl ester

cyclobutylmethyl 4-methylbenzenesulfonate

cyclobutanemethanol