1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Base Information

Chemical Name:1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS No.:1007110-53-3
Molecular Formula:C11 H21BN2O3
Molecular Weight:222.095
Hs Code.:2933199090
European Community (EC) Number:813-200-5
DSSTox Substance ID:DTXSID40682349
Wikidata:Q82606686
Mol file:1007110-53-3.mol

Synonyms:1007110-53-3;1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-ETHYLPYRAZOLE-5-BORONIC ACID PINACOL ESTER;1-ethylpyrazole-5-boronic acid, pinacol ester;1-ethyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-ETHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZOLE;1-ethylpyrazole-5-boronic acid,pinacol ester;MFCD16659009;(1-ETHYL-1H-PYRAZOL-5-YL)BORONIC ACID PINACOL ESTER;SCHEMBL1530333;DTXSID40682349;PKJCXHILXIEALN-UHFFFAOYSA-N;AMY32812;STL415200;AKOS015921212;CS-W001067;PB21399;AS-32464;SY021888;FT-0749610;EN300-135150;1-ETHYLPYRAZOLE-5-BORONICACIDPINACOLESTER;A854097;Z1336745147;1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-d ioxaborolan-2-yl)-1H-pyrazole;1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;1H-Pyrazole,1-ethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-;1H-PYRAZOLE, 1-ETHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-

Suppliers and Price of 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Ethylpyrazole-5-boronicAcidPinacolEster
100mg
$ 45.00

Synthonix
1-Ethylpyrazole-5-boronicacidpinacolester 97.0%
50g
$ 820.00

Synthonix
1-Ethylpyrazole-5-boronicacidpinacolester 97.0%
1g
$ 40.00

Synthonix
1-Ethylpyrazole-5-boronicacidpinacolester 97.0%
5g
$ 120.00

SynQuest Laboratories
1-Ethylpyrazole-5-boronic acid, pinacol ester
5 g
$ 200.00

SynQuest Laboratories
1-Ethylpyrazole-5-boronic acid, pinacol ester
1 g
$ 125.00

SynQuest Laboratories
1-Ethylpyrazole-5-boronic acid, pinacol ester
25 g
$ 750.00

Medical Isotopes, Inc.
1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 95+%
5 g
$ 665.00

Matrix Scientific
1-Ethylpyrazole-5-boronic acid pinacol ester
1g
$ 111.00

Matrix Scientific
1-Ethylpyrazole-5-boronic acid pinacol ester
5g
$ 309.00

Total 32 raw suppliers

Chemical Property of 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Chemical Property:

Boiling Point:322.6±15.0 °C(Predicted)
PKA:1.96±0.10(Predicted)
PSA：36.28000
Density:1.04±0.1 g/cm3(Predicted)
LogP:1.20220
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:222.1539580
Heavy Atom Count:16
Complexity:255

Purity/Quality:

99%, ^*data from raw suppliers

1-Ethylpyrazole-5-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=NN2CC
Uses 1-Ethylpyrazole-5-boronic acid, pinacol ester

Technology Process of 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

There total 1 articles about 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61676-62-8
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 2817-71-2
1-ethyl-1H-pyrazole

: 1007110-53-3
1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Guidance literature:: 1-methyl-1H-pyrazole; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 1h;

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 1.25h;

Reference yield: 80.1%

: 1007110-53-3
1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: C₁₈H₁₄ClF₃N₄O₂

: (S)-(5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)(3-((2-(1-ethyl-1H-pyrazol-5-yl)-5-fluoropyridin-4-yl)oxy)azetidin-1-yl)methanone

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium acetate; XPhos; In 1,4-dioxane; at 100 ℃; for 2h; Inert atmosphere;

Reference yield: 77.0%

: 1007110-53-3
1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 3-(8-(bis(4-methoxybenzyl)amino)-5-bromo-2-((2,6-difluorophenyl) (hydroxy)methyl)-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)benzonitrile

: 3-(8-amino-2-((2,6-difluorophenyl)(hydroxy)methyl)-5-(1-ethyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)benzonitrile

Guidance literature:: 1-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 3-(8-(bis(4-methoxybenzyl)amino)-5-bromo-2-((2,6-difluorophenyl) (hydroxy)methyl)-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)benzonitrile; With potassium phosphate; dicyclohexyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphino-(2′-aminobiphenyl-2-yl)(chloro)palladium; In 1,4-dioxane; water; at 100 ℃; for 2h;

With trifluoroacetic acid; at 80 ℃; for 0.333333h;