1-Ethylpyrazole

Base Information

• Chemical Name: 1-Ethylpyrazole
• CAS No.: 2817-71-2
• Molecular Formula: C5H8N2
• Molecular Weight: 96.1319
• Hs Code.: 2933199090
• Mol file: 2817-71-2.mol

Synonyms:Pyrazole,1-ethyl- (6CI,7CI,8CI);1-Ethylpyrazole;N-Ethylpyrazole;1-Ethyl-1H-pyrazole;

Chemical Property of 1-Ethylpyrazole

Chemical Property:

• Vapor Pressure: 7.73mmHg at 25°C
• Melting Point: 82.75°C (estimate)
• Refractive Index: 1.517
• Boiling Point: 140.234 °C at 760 mmHg
• PKA: 2.27±0.10(Predicted)
• Flash Point: 38.612 °C
• PSA: 17.82000
• Density: 0.975 g/cm³
• LogP: 0.90300
• Storage Temp.: Room temperature.

Purity/Quality:

98.0% min ^*data from raw suppliers

1-Ethyl-1H-Pyrazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Ethylpyrazole

There total 4 articles about 1-Ethylpyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

NH-pyrazole (288-13-1) + ethyl iodide (75-03-6) → 1-ethyl-1H-pyrazole (2817-71-2)

Guidance literature:

With potassium hydroxide; tetrabutylammomium bromide; at 0 ℃; for 24h;

Reference yield: 93.0%

NH-pyrazole (288-13-1) + ethyl bromide (74-96-4) → 1-ethyl-1H-pyrazole (2817-71-2)

Guidance literature:

NH-pyrazole; With potassium hydroxide; In dimethyl sulfoxide; at 80 ℃; for 1h;

ethyl bromide; In dimethyl sulfoxide; at 20 ℃; for 4h;

DOI:10.1134/S1070428006040117

Reference yield:

NH-pyrazole (288-13-1) + 2-bromoethanol (540-51-2) → 1-ethyl-1H-pyrazole (2817-71-2)

Guidance literature:

NH-pyrazole; With potassium hydroxide; In dimethyl sulfoxide; at 80 ℃; for 0.5h;

2-bromoethanol; In dimethyl sulfoxide;

upstream raw materials:

NH-pyrazole

ethyl bromide

ethyl iodide

2-bromoethanol

Downstream raw materials:

C₈H₁₅N₃

N-ethyl-1H-5-methylpyrazole-4-carboxaldehyde

4-(4-bromo-1-ethyl-1H-pyrazol-5-yl)-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide

4-(4-chloro-1-ethyl-1H-pyrazol-5-yl)-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide

Refernces

• 1、 -. "Benzyl pyrazole ionic liquid compound as well as preparation method and application thereof". Paragraph 0025-0027. . Retrieved 2021/05/12.
• 2、 He, Tong,Wang, Ye Feng,Zeng, Jing Hui. "Pyrazolium-based electrolyte for solid-state dye-sensitized solar cells with high fill factor and open-circuit voltage". . p. 8235 - 8244. Retrieved 2016/09/09.