Desmethyl Doxylamine

Base Information

Chemical Name:Desmethyl Doxylamine
CAS No.:1221-70-1
Molecular Formula:C8H14N2O3
Molecular Weight:256.348
Hs Code.:
UNII:O977IVG217
Mol file:1221-70-1.mol

Synonyms:Desmethyl Doxylamine;1221-70-1;Deschloro carbinoxamine;N,N-dimethyl-2-[phenyl(pyridin-2-yl)methoxy]ethanamine;O977IVG217;N,N-Dimethyl-2-(phenyl(pyridin-2-yl)methoxy)ethanamine;Ethanamine, N,N-dimethyl-2-(phenyl-2-pyridinylmethoxy)-;N,N-Dimethyl-2-(phenyl(pyridin-2-yl)methoxy)ethan-1-amine;(R)-Desmethyl Doxylamine;N,N-dimethyl-2-(phenyl(pyridine-2-yl)methoxy)ethan-1-amine;starbld0028852;Desmethyl doxylamine [USP];UNII-O977IVG217;MFCD31562535;DESMETHYL DOXYLAMINE [USP IMPURITY];FT-0699404;2-[alpha-[2-(Dimethylamino)ethoxy]benzyl]pyridine;EN300-22933606;N,N-Dimethyl-2-(phenyl-2-pyridinylmethoxy)ethanamine;dimethyl({2-[phenyl(pyridin-2-yl)methoxy]ethyl})amine;Pyridine, 2-(alpha-(2-(trimethylamino)ethoxy)benzyl)-;PYRIDINE, 2-(.ALPHA.-(2-(TRIMETHYLAMINO)ETHOXY)BENZYL)-;N,N-Dimethyl-2-((1RS)-1-phenyl-1-(pyridin-2-yl)methoxy)ethanamine

Suppliers and Price of Desmethyl Doxylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DesmethylDoxylamine
1g
$ 1390.00

Biosynth Carbosynth
N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)methoxy)ethanamine
2 g
$ 330.00

Biosynth Carbosynth
N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)methoxy)ethanamine
1 g
$ 175.00

Biosynth Carbosynth
N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)methoxy)ethanamine
500 mg
$ 87.50

Biosynth Carbosynth
N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)methoxy)ethanamine
250 mg
$ 50.00

Total 10 raw suppliers

Chemical Property of Desmethyl Doxylamine

Chemical Property:

PSA：25.36000
LogP:2.74920
Storage Temp.:Refrigerator, under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:256.157563266
Heavy Atom Count:19
Complexity:239

Purity/Quality:

99%, ^*data from raw suppliers

DesmethylDoxylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=N2
Uses Desmethyl Doxylamine is an impurity of Doxylamine (D562000), an H1 Histamine receptor antagonist used as a antihistaminic and sedative agent.

Technology Process of Desmethyl Doxylamine

There total 3 articles about Desmethyl Doxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 107-99-3
2-(dimethylamino)ethyl chloride

: 31796-72-2
phenyl(2-pyridinyl)methanol

: 1221-70-1
2-[α-(2-dimethylamino-ethoxy)-benzyl]-pyridine

Guidance literature:: With sodium t-butanolate; In 5,5-dimethyl-1,3-cyclohexadiene; toluene; for 7h; Reagent/catalyst; Time; Inert atmosphere; Reflux;