2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester

Base Information

Chemical Name:2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester
CAS No.:1260231-89-7
Molecular Formula:C16H28BNO5S
Molecular Weight:339.264
Hs Code.:
Mol file:1260231-89-7.mol

Synonyms:2-(tert-butylaMino)sulfonyl-phenylboronic acid pinacol ester

Suppliers and Price of 2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester

Chemical Property:

PSA：73.01000
LogP:3.53430

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester

There total 2 articles about 2-(Tert-butylamino)sulfonyl-phenylboronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73183-34-3
bis(pinacol)diborane

: 138733-50-3
N-(1,1-dimethylethyl)-2-bromobenzenesulfonamide

: 1260231-89-7
N-(t-butyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzenesulfonamide

Guidance literature:: palladium diacetate; In N,N-dimethyl-formamide; at 70 ℃; for 50h; Inert atmosphere; Reflux;

Reference yield:

: 2905-25-1
o-bromobenzenesulfonyl chloride

: 1260231-89-7
N-(t-butyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 0.02 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: potassium acetate / palladium diacetate / N,N-dimethyl-formamide / 50 h / 70 °C / Inert atmosphere; Reflux

With potassium acetate; palladium diacetate; In dichloromethane; N,N-dimethyl-formamide;

Reference yield: 97.0%

: 1260231-89-7
N-(t-butyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)benzenesulfonamide

: ethyl 5-(2-(4-chloro-6-oxopyrimidin-1(6H)-yl)acetyl)-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate

: ethyl 5-(2-(4-(2-(N-(tert-butyl)sulfamoyl)phenyl)-6-oxopyrimidin-1(6H)-yl)acetyl)-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate; In 1,2-dimethoxyethane; water; at 90 ℃; for 6h; Inert atmosphere;