1H-INDENE-2-BORONIC ACID PINACOL ESTER

Base Information

• Chemical Name: 1H-INDENE-2-BORONIC ACID PINACOL ESTER
• CAS No.: 749869-98-5
• Molecular Formula: C15H19BO2
• Molecular Weight: 242.12
• Mol file: 749869-98-5.mol

Synonyms:1H-INDENE-2-BORONIC ACID PINACOL ESTER;2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 1H-INDENE-2-BORONIC ACID PINACOL ESTER

Chemical Property:

• Melting Point: 72-80°C
• Boiling Point: 293.4±50.0 °C(Predicted)
• PSA: 18.46000
• Density: 1.06±0.1 g/cm3(Predicted)
• LogP: 3.25750
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

1H-Indene-2-boronic acid pinacol ester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-INDENE-2-BORONIC ACID PINACOL ESTER

There total 5 articles about 1H-INDENE-2-BORONIC ACID PINACOL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1-indene (95-13-6) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (749869-98-5)

Guidance literature:

With bis(cyclopentadienyl)dihydrozirconium; In toluene; at 25 ℃; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201908931

Reference yield: 69.0%

2-bromoindene (10485-09-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (749869-98-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; triethylamine; In 1,4-dioxane; at 80 ℃; for 5.5h; Inert atmosphere; Schlenk technique;

Reference yield: 57.0%

C12H13NO2 (1268936-41-9) + bis(pinacol)diborane (73183-34-3) → 2-(1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (749869-98-5)

Guidance literature:

With iron(II) triflate; [2,2]bipyridinyl; lithium methanolate; In toluene; at 100 ℃; for 15h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1021/acs.orglett.0c01937

upstream raw materials:

1-indene

bis(pinacol)diborane

2-bromoindene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Downstream raw materials:

2-([1,1'-biphenyl]-4-yl)-1H-indene

Refernces

• 1、 Geng, Shasha,Zhang, Juan,Chen, Shuo,Liu, Zhengli,Zeng, Xiaoqin,He, Yun,Feng, Zhang. "Development and Mechanistic Studies of Iron-Catalyzed Construction of Csp2-B Bonds via C-O Bond Activation". . p. 5582 - 5588. Retrieved 2020/07/08.
• 2、 -. "PROCESS FOR THE PREPARATION OF METALLOCENE COMPLEXES". Page/Page column 20; 21. . Retrieved 2013/07/05.