AZD3514

Base Information

Chemical Name:AZD3514
CAS No.:1240299-33-5
Molecular Formula:C25H32F3N7O2
Molecular Weight:519.57
Hs Code.:
Mol file:1240299-33-5.mol

Synonyms:S7040,AZD 3514;6-(4-{4-[2-(4-acetylpiperazin-1-yl)ethoxy]phenyl}piperidin-1-yl)-3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine;1-(4-(2-(4-(1-(3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)ethanone;1-[4-[2-[4-[1-[3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-1-yl]ethanone;AZD3514;

Suppliers and Price of AZD3514

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
AZD-3514
10mg
$ 460.00

DC Chemicals
AZD3514 >98%
1 g
$ 1600.00

DC Chemicals
AZD3514 >98%
250 mg
$ 800.00

Crysdot
AZD3514 98+%
10mg
$ 91.00

Crysdot
AZD3514 98+%
50mg
$ 260.00

Crysdot
AZD3514 98+%
100mg
$ 423.00

Crysdot
AZD3514 98+%
5mg
$ 52.00

Biorbyt Ltd
AZD3514 >98%
1 g
$ 2395.30

Biorbyt Ltd
AZD3514 >98%
250 mg
$ 1208.70

Biorbyt Ltd
AZD3514 >98%
100 mg
$ 615.40

Total 23 raw suppliers

Chemical Property of AZD3514

Chemical Property:

Appearance/Colour:White to off-white solid
Boiling Point:669.5±65.0 °C(Predicted)
PKA:6.31±0.10(Predicted)
PSA：79.09000
Density:1.41±0.1 g/cm3(Predicted)
LogP:2.07650
Solubility.:≥24.45 mg/mL in DMSO; insoluble in H2O; ≥46.4 mg/mL in EtOH

Purity/Quality:

99%, ^*data from raw suppliers

AZD-3514 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of AZD3514

There total 13 articles about AZD3514 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1166819-37-9
1-(4-(2-(4-(1-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]-pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)-ethanone

: 1240299-33-5
1-(4-(2-(4-(1-(3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)ethanone

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 22 - 50 ℃; for 10h; under 3750.38 Torr; Autoclave;
DOI:10.1016/j.bmcl.2013.02.056

Reference yield: 88.0%

: 1166819-39-1
6-[4-[4-[3-(4-acetylpiperazin-1-yl)propoxy]phenyl]piperidin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine

: 1240299-33-5
1-(4-(2-(4-(1-(3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)ethanone

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 50 ℃; for 10h; under 3750.38 Torr; Product distribution / selectivity; Autoclave;