Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate

Base Information

Chemical Name:Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate
CAS No.:1089278-51-2
Molecular Formula:C16H13F2NO4
Molecular Weight:321.28
Hs Code.:
Mol file:1089278-51-2.mol

Synonyms:Methyl 3-(o-(hexadecyloxy)phenyl)-3-oxopropionate;methyl 3-{[(2,6-difluorophenyl)amino]carbonyl}-4-(methyloxy)benzoate;methyl 3-[2-(hexadecyloxy)phenyl]-3-oxopropanoate;

Suppliers and Price of Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
methyl3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate
100mg
$ 265.00

Total 8 raw suppliers

Chemical Property of Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate

Chemical Property:

Boiling Point:381.0±42.0 °C(Predicted)
PKA:11.10±0.70(Predicted)
PSA：68.12000
Density:1.346±0.06 g/cm3(Predicted)
LogP:3.39630

Purity/Quality:

≥95% ^*data from raw suppliers

methyl3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate

There total 1 articles about Methyl 3-(2,6-difluorophenylcarbamoyl)-4-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 90183-43-0
2-methoxy-5-(methoxycarbonyl)benzoic acid

: 5509-65-9
2,6-difluoroaniline

: 1089278-51-2
methyl 3-{[(2,6-difluorophenyl)amino]carbonyl}-4-(methyloxy)benzoate

Guidance literature:: 2-methoxy-5-(methoxycarbonyl)benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 2h;

2,6-difluoroaniline; With pyridine; dmap; In dichloromethane; for 18h;

Reference yield:

: 13036-57-2
2-chloro-4-methylpyrimidine

: 1089278-51-2
methyl 3-{[(2,6-difluorophenyl)amino]carbonyl}-4-(methyloxy)benzoate

: 1089278-52-3
5-[(2-Chloro-4-pyrimidinyl)acetyl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide

: 5-[(E)-2-(2-chloro-4-pyrimidinyl)-1-hydroxyethenyl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide

Guidance literature:: 2-chloro-4-methylpyrimidine; methyl 3-{[(2,6-difluorophenyl)amino]carbonyl}-4-(methyloxy)benzoate; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h;

With ammonium chloride; In tetrahydrofuran; water;