1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde

Base Information

Chemical Name:1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde
CAS No.:857070-65-6
Molecular Formula:C22H27N5O3
Molecular Weight:409.488
Hs Code.:
Mol file:857070-65-6.mol

Synonyms:3-(3-hydroxy-6-methylpyridin-2-ylmethyl)-2-(3-morpholin-4-ylpropylamino)-3H-benzoimidazole-5-carbaldehyde;5-(3-AMINOCARBONYLPHENYL)-3-METHOXYPHENOL;

Suppliers and Price of 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde

Chemical Property:

PSA：95.74000
LogP:1.80010

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde

There total 5 articles about 1-((3-hydroxy-6-Methylpyridin-2-yl)Methyl)-2-((3-Morpholinopropyl)aMino)-1H-benzo[d]iMidazole-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 857067-38-0
2-[6-hydroxymethyl-2-(3-morpholin-4-ylpropylamino)benzoimidazol-1-ylmethyl]-6-methylpyridin-3-ol

: 857070-65-6
3-(3-hydroxy-6-methylpyridin-2-ylmethyl)-2-(3-morpholin-4-ylpropylamino)-3H-benzoimidazole-5-carbaldehyde

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1021/jm701284j

Reference yield:

: 857070-67-8
[2-(3-morpholin-4-ylpropylamino)-3H-benzoimidazol-5-yl]methanol

: 857070-65-6
3-(3-hydroxy-6-methylpyridin-2-ylmethyl)-2-(3-morpholin-4-ylpropylamino)-3H-benzoimidazole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

2: manganese(IV) oxide / dichloromethane / 12 h / 20 °C

With manganese(IV) oxide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 857070-66-7
(2-chloro-3H-benzoimidazol-5-yl)methanol

: 857070-65-6
3-(3-hydroxy-6-methylpyridin-2-ylmethyl)-2-(3-morpholin-4-ylpropylamino)-3H-benzoimidazole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 4 h / 125 °C

2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

3: manganese(IV) oxide / dichloromethane / 12 h / 20 °C

With manganese(IV) oxide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;