1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-

Base Information

Chemical Name:1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-
CAS No.:83552-41-4
Molecular Formula:C7H11NO2S2.ClH
Molecular Weight:241.763
Hs Code.:
UNII:26EUN2ME49

Synonyms:26EUN2ME49;83552-41-4;UNII-26EUN2ME49;1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-;1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, hydrochloride, (S)-;F89543;(S)-1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride;1,4-DITHIA-7-AZASPIRO(4,4)NONANE-8-(S)-CARBOXYLIC ACID HYDROCHLORIDE

Suppliers and Price of 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:240.9997987
Heavy Atom Count:13
Complexity:204

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSC2(S1)CC(NC2)C(=O)O.Cl
Isomeric SMILES:C1CSC2(S1)C[C@H](NC2)C(=O)O.Cl

Technology Process of 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)-

There total 1 articles about 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid hydrochloride, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64187-47-9
1-benzyloxycarbonyl-4-keto-L-proline

: 83552-41-4
(S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃*Et₂O / CH₂Cl₂ / Ambient temperature

2: HCl / acetic acid / 1 h / Heating

With hydrogenchloride; boron trifluoride diethyl etherate; In dichloromethane; acetic acid;
DOI:10.1021/jm00401a014

Reference yield:

: 83552-41-4
(S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, hydrochloride

: 83602-05-5,83507-88-4
Spiraprilat

Guidance literature:: Multi-step reaction with 3 steps

1: HCl / 1.) -30 deg C, 2 h, 2.) room temperature, 24 h

2: diphenyl phosphorazidate, Et₃N / dimethylformamide / 1.) 0 deg C, 3 h, 2.) room temperature, 19 h

3: 1N NaOH / ethanol / 4 h

With hydrogenchloride; sodium hydroxide; diphenyl phosphoryl azide; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00401a014

Reference yield:

: 83552-41-4
(S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, hydrochloride

: 83623-49-8
(S)-7-[[Hydroxy(4-phenylbutyl)phosphinyl)acetyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: HCl / 1.) -30 deg C, 2 h, 2.) room temperature, 24 h

2: 92 percent / carbodiimidazole, Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

3: 84 percent / 1N NaOH / 0.5 h

With hydrogenchloride; sodium hydroxide; triethylamine; 1,1'-carbonyldiimidazole; In dichloromethane;
DOI:10.1021/jm00401a014