(S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid

Base Information

Chemical Name:(S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid
CAS No.:1004316-92-0
Molecular Formula:C17H28N4O4S
Molecular Weight:384.5
Hs Code.:
Mol file:1004316-92-0.mol

Synonyms:(S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid;(alphaS)-alpha-[[[Methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]-4-morpholinebutanoic acid

Suppliers and Price of (S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2-{[Methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanoicAcid
250mg
$ 2100.00

Total 18 raw suppliers

Chemical Property of (S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid

Chemical Property:

Boiling Point:640.0±55.0 °C(Predicted)
PKA:3.98±0.10(Predicted)
PSA：123.24000
Density:1.238±0.06 g/cm3(Predicted)
LogP:1.91220

Purity/Quality:

99%, ^*data from raw suppliers

(2S)-2-{[Methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid

There total 9 articles about (S)-2-(3-((2-isopropylthiazol-4-yl)Methyl)-3-Methylureido)-4-Morpholinobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1004316-96-4
C₂₄H₃₄N₄O₄S

: 1004316-92-0
C₁₇H₂₈N₄O₄S

Guidance literature:: C₂₄H₃₄N₄O₄S; With sodium hydroxide; ethanol; water; at 25 ℃; for 1h;

With hydrogenchloride; water; In dichloromethane; Product distribution / selectivity;

Reference yield:

: 1004316-91-9
methyl (S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanoate

: 1004316-92-0
C₁₇H₂₈N₄O₄S

Guidance literature:: methyl (S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanoate; With lithium hydroxide; In tetrahydrofuran; water; at 25 ℃; for 1h;

With hydrogenchloride; water; In tetrahydrofuran; Product distribution / selectivity;

Reference yield:

: 1004316-93-1
3-methyl-1-[(3S)-2-oxooxolan-3-yl]-3-{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}urea

: 1004316-92-0
C₁₇H₂₈N₄O₄S

Guidance literature:: Multi-step reaction with 4 steps

1.1: water; sodium hydroxide / ethanol / 1 h / 0 - 25 °C

1.2: 16 h

2.1: triethylamine / dimethyl sulfoxide / 0.5 h

2.2: 1 h / 0 - 10 °C

3.1: acetic acid; sodium tris(acetoxy)borohydride / acetonitrile / 12 h / Cooling

4.1: water; sodium hydroxide / ethanol / 1 h / 0 - 25 °C

With water; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; sodium hydroxide; In ethanol; dimethyl sulfoxide; acetonitrile;