Diethyl 2-cyclopentylidenepropanedioate

Base Information

Chemical Name:Diethyl 2-cyclopentylidenepropanedioate
CAS No.:41589-42-8
Molecular Formula:C12H18O4
Molecular Weight:226.273
Hs Code.:
DSSTox Substance ID:DTXSID601260128
Nikkaji Number:J791.675B
Mol file:41589-42-8.mol

Synonyms:Diethyl 2-cyclopentylidenepropanedioate;Propanedioic acid, 2-cyclopentylidene-, 1,3-diethyl ester;41589-42-8;1,3-diethyl 2-cyclopentylidenepropanedioate;2-Cyclopentylidenemalonic acid diethyl ester;diethyl cyclopentylidenemalonate;SCHEMBL3200633;DTXSID601260128;AKOS024335788

Suppliers and Price of Diethyl 2-cyclopentylidenepropanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Diethyl 2-cyclopentylidenepropanedioate

Chemical Property:

Refractive Index:1.4724 (estimate)
Boiling Point:327.88°C (rough estimate)
PSA：52.60000
Density:1.0616
LogP:1.98320
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:226.12050905
Heavy Atom Count:16
Complexity:276

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(=C1CCCC1)C(=O)OCC

Technology Process of Diethyl 2-cyclopentylidenepropanedioate

There total 12 articles about Diethyl 2-cyclopentylidenepropanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 120-92-3
cyclopentanone

: 105-53-3
diethyl malonate

: 41589-42-8
2-cyclopentylidenemalonic acid diethyl ester

Guidance literature:: cyclopentanone; diethyl malonate; With titanium tetrachloride; In tetrahydrofuran; tetrachloromethane; at 0 ℃; for 0.5h;

With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 73h;
DOI:10.1021/jm049924d

Reference yield:

: 14064-08-5
diethyl 2-(phenylthio)malonate

: 41589-42-8
2-cyclopentylidenemalonic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / NaH / tetrahydrofuran / 24 h / Heating

2: m-CPBA / CH₂Cl₂ / 1 h / 0 °C

3: 0.75 g / toluene / 2 h / Heating

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo970107d

Reference yield:

: 3558-06-3
cyclopentyl tosylate

: 41589-42-8
2-cyclopentylidenemalonic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / NaH / tetrahydrofuran / 24 h / Heating

2: m-CPBA / CH₂Cl₂ / 1 h / 0 °C

3: 0.75 g / toluene / 2 h / Heating

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jo970107d