Ethanone, 2-broMo-1-(2-iodophenyl)-

Base Information

• Chemical Name: Ethanone, 2-broMo-1-(2-iodophenyl)-
• CAS No.: 113258-84-7
• Molecular Formula: C8H6BrIO
• Molecular Weight: 324.944
• Hs Code.: 2914790090
• Mol file: 113258-84-7.mol

Synonyms:2-Bromo-2'-iodoacetophenone

Chemical Property of Ethanone, 2-broMo-1-(2-iodophenyl)-

Chemical Property:

• Boiling Point: 162-164 °C(Press: 6 Torr)
• PSA: 17.07000
• Density: 2.080±0.06 g/cm3(Predicted)
• LogP: 2.86880

Purity/Quality:

99.90% ^*data from raw suppliers

2-IodophenacylBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanone, 2-broMo-1-(2-iodophenyl)-

There total 7 articles about Ethanone, 2-broMo-1-(2-iodophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-iodoacetophenone (2142-70-3) → 2-bromo-1-(2-iodophenyl)ethanone (113258-84-7)

Guidance literature:

With copper(ll) bromide; In ethyl acetate; for 1.5h; Heating / reflux;

Reference yield: 90.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-Iodobenzoic acid (88-67-5) → 2-bromo-1-(2-iodophenyl)ethanone (113258-84-7)

Guidance literature:

2-Iodobenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;

diazomethane; In diethyl ether; dichloromethane; at 0 ℃; for 1h;

With hydrogen bromide; In diethyl ether; dichloromethane; Further stages.;

DOI:10.1021/jo800618q

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2-Iodobenzoyl chloride (609-67-6) → 2-bromo-1-(2-iodophenyl)ethanone (113258-84-7)

Guidance literature:

With diethyl ether; anschliessend Behandeln mit wss. HBr und Aether;

DOI:10.1021/jo01169a001

upstream raw materials:

diazomethane

2-Iodobenzoyl chloride

2-iodoacetophenone

2-Iodobenzoic acid

Downstream raw materials:

[4-amino-2-(4-methoxy-phenylamino)-thiazol-5-yl]-(2-iodo-phenyl)-methanone

2-amino-5-(2-iodophenyl)imidazole-1-carboxylic acid tert-butyl ester

5-bromo-2-methyl-1-(2-iodophenacyl)-4-nitroimidazole

4-bromo-2-methyl-1-(2-iodoophenacyl)-5-nitroimidazole