GLPG0634

Base Information

Chemical Name:GLPG0634
CAS No.:1206101-20-3
Molecular Formula:C23H18N6O2
Molecular Weight:410.435
Hs Code.:
Mol file:1206101-20-3.mol

Synonyms:CS-1887;GLPG634 analog;Filgotinib analog;GLPG0634 analogue;GLPG0634 analog, Filgotinib analog;N-[5-[4-[(6-cyano-3-pyridinyl)Methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxaMide;N-(5-(4-((6-cyanopyridin-3-yl)methoxy)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[5-[4-[(6-cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-;N-[5-[4-[(6-Cyano-3-pyridinyl)Methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl] cyclopropanecarboxaMide (GLPG0634);N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-cyclopropanecarboxamide GLPG0634 analogue

Suppliers and Price of GLPG0634

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
2.5mg
$ 185.00

DC Chemicals
GLPG0634analogue >98%
100 mg
$ 450.00

Crysdot
GLPG0634analog 98+%
10mg
$ 298.00

Crysdot
GLPG0634analog 98+%
5mg
$ 172.00

Crysdot
GLPG0634analog 98+%
50mg
$ 1260.00

ChemScene
GLPG0634analog 98.58%
50mg
$ 600.00

ChemScene
GLPG0634analog 98.58%
5mg
$ 100.00

ChemScene
GLPG0634analog 98.58%
10mg
$ 280.00

ApexBio Technology
GLPG0634analogue
5mg
$ 228.00

Total 30 raw suppliers

Chemical Property of GLPG0634

Chemical Property:

PSA：108.43000
LogP:3.01238
Solubility.:insoluble in EtOH; insoluble in H2O; ≥31.67 mg/mL in DMSO with gentle warming

Purity/Quality:

99%, ^*data from raw suppliers

N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide, is an orally-available, selective inhibitor of JAK1 (Janus kinase 1), used for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.

Technology Process of GLPG0634

There total 1 articles about GLPG0634 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1142943-96-1
cyclopropanecarboxylic acid (5-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-amide

: 1206101-28-1
5-[4-(4, 4, 5, 5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxymethyl]-pyridine-2-carbonitrile

: 1206101-20-3
GLPG₀₆₃₄

Guidance literature:: With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; water; at 90 ℃; Inert atmosphere;