7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione

Base Information

Chemical Name:7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione
CAS No.:1260088-71-8
Molecular Formula:C₈H₁₀N₂O₃
Molecular Weight:182.179
Hs Code.:2933599590
Mol file:1260088-71-8.mol

Synonyms:7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione;7,7-DiMethyl-5,7-dihydrofuro[3,4-d]pyriMidine-2,4(1H,3H)-dione

Suppliers and Price of 7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
7,7-Dimethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,4-dione 99%
1g
$ 885.00

Matrix Scientific
7,7-Dimethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,4-dione 99%
500mg
$ 553.00

Matrix Scientific
7,7-Dimethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,4-dione 99%
250mg
$ 346.00

Crysdot
7,7-Dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione 95+%
5g
$ 1200.00

Crysdot
7,7-Dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione 95+%
1g
$ 399.00

AK Scientific
7,7-Dimethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,4-dione
250mg
$ 437.00

Total 5 raw suppliers

Chemical Property of 7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione

Chemical Property:

PKA:9.94±0.40(Predicted)
PSA：74.95000
Density:1.36±0.1 g/cm3(Predicted)
LogP:-0.17150

Purity/Quality:

97% ^*data from raw suppliers

7,7-Dimethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,4-dione 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione

There total 2 articles about 7,7-DiMethyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyriMidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 75-44-5
phosgene

: 1260088-70-7
methyl 4-amino-5,5-dimethyl-2,5-dihydrofuran-3-carboxylate

: 1260088-71-8
7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With pyridine; In 1,2-dichloro-ethane; toluene; at 0 ℃; for 3h;

Reference yield:

: methyl 5,5-dimethyl-4-oxotetrahydrofuran-3-carboxylate

: 1260088-71-8
7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonium acetate / methanol / 20 h / Reflux

2.1: pyridine / 1,2-dichloro-ethane; toluene / 3 h / 0 °C

2.2: 19 h / 0 - 50 °C

With pyridine; ammonium acetate; In methanol; 1,2-dichloro-ethane; toluene;
DOI:10.1021/jm200215y

Reference yield: 82.0%

: 1260088-71-8
7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione

: 1260088-72-9
2,4-dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

Guidance literature:: 7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione; With trichlorophosphate; In 1,2-dichloro-ethane; at 80 ℃; for 20h;

With sodium hydrogencarbonate; In dichloromethane; water;