2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

Base Information

Chemical Name:2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine
CAS No.:1260088-72-9
Molecular Formula:C8H8Cl2N2O
Molecular Weight:219.07
Hs Code.:2934999090
DSSTox Substance ID:DTXSID201192688
Mol file:1260088-72-9.mol

Synonyms:2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine;1260088-72-9;2,4-dichloro-7,7-dimethyl-5H-furo[3,4-d]pyrimidine;MFCD19688042;SCHEMBL2707029;2,4-dichloro-7,7-dimethyl-5H,7H-furo[3,4-d]pyrimidine;AMY5318;IGGHWEUEJMUGHP-UHFFFAOYSA-N;2,4-dichloro-5,7-dihydro-7,7-dimethylFuro[3,4-d]pyrimidine;DTXSID201192688;CS2049;AKOS022182231;AC-31212;DS-17050;CS-0036672;FT-0751461;EN300-227495;A889873;A1-02094;Z1269242829;Furo[3,4-d]pyrimidine, 2,4-dichloro-5,7-dihydro-7,7-dimethyl-

Suppliers and Price of 2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine
50mg
$ 220.00

SynQuest Laboratories
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine
1 g
$ 1592.00

Matrix Scientific
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 99%
1g
$ 1420.00

Matrix Scientific
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 99%
250mg
$ 555.00

Matrix Scientific
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 99%
500mg
$ 887.00

Crysdot
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 98%
1g
$ 980.00

Crysdot
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 98%
100mg
$ 246.00

Crysdot
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine 98%
250mg
$ 392.00

Alichem
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine
1g
$ 767.72

AK Scientific
2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine
1g
$ 1366.00

Total 14 raw suppliers

Chemical Property of 2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

Chemical Property:

Boiling Point:317.6±42.0 °C(Predicted)
PKA:-3.37±0.40(Predicted)
PSA：35.01000
Density:1.383±0.06 g/cm3(Predicted)
LogP:2.54870
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:218.0013683
Heavy Atom Count:13
Complexity:212

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2=C(CO1)C(=NC(=N2)Cl)Cl)C
Uses 2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine is used for preparation and study of pharmacokinetics, and antitumor activity of dihydrofuro[3,4-d]pyrimidines as inhibitors of mammalian target of rapamycin kinase.

Technology Process of 2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

There total 1 articles about 2,4-Dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1260088-71-8
7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione

: 1260088-72-9
2,4-dichloro-7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

Guidance literature:: 7,7-dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione; With trichlorophosphate; In 1,2-dichloro-ethane; at 80 ℃; for 20h;

With sodium hydrogencarbonate; In dichloromethane; water;