7-Chloroquinoline-2-carbaldehyde

Base Information

Chemical Name:7-Chloroquinoline-2-carbaldehyde
CAS No.:59394-27-3
Molecular Formula:C10H6ClNO
Molecular Weight:191.617
Hs Code.:
Nikkaji Number:J3.495.358I

Synonyms:7-chloroquinoline-2-carbaldehyde;59394-27-3;7-Chloro-quinoline-2-carbaldehyde;SCHEMBL3748357;LZJIPAFEFGRTQS-UHFFFAOYSA-N;7-chloroquinoline-2-carboxaldehyde;MFCD06407627;AKOS006295332;SB67564;AM806098;AS-39500;CS-0187266;J3.495.358I;EN300-344778;Z1198168652

Suppliers and Price of 7-Chloroquinoline-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
7-Chloroquinoline-2-carbaldehyde
1g
$ 462.24

American Custom Chemicals Corporation
7-CHLOROQUINOLINE-2-CARBALDEHYDE 95.00%
5MG
$ 503.05

American Custom Chemicals Corporation
7-CHLOROQUINOLINE-2-CARBALDEHYDE 95.00%
5G
$ 3423.00

Chemenu
7-Chloroquinoline-2-carbaldehyde 95%
1g
$ 795.00

Crysdot
7-Chloroquinoline-2-carbaldehyde 95+%
1g
$ 850.00

Labseeker
7-chloroquinoline-2-carbaldehyde 95
25g
$ 3667.00

TRC
7-Chloroquinoline-2-Carbaldehyde
50mg
$ 90.00

Total 4 raw suppliers

Chemical Property of 7-Chloroquinoline-2-carbaldehyde

Chemical Property:

Boiling Point:349.3±22.0 °C(Predicted)
PSA：29.96000
Density:1.364±0.06 g/cm3(Predicted)
LogP:2.70070
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:191.0137915
Heavy Atom Count:13
Complexity:197

Purity/Quality:

99%, ^*data from raw suppliers

7-Chloroquinoline-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC2=C1C=CC(=N2)C=O)Cl

Technology Process of 7-Chloroquinoline-2-carbaldehyde

There total 3 articles about 7-Chloroquinoline-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 4965-33-7
2-methyl-7-chloroquinoline

: 59394-27-3
7-chloro-quinoline-2-carbaldehyde

Guidance literature:: With selenium(IV) oxide; In 1,4-dioxane; at 60 ℃; Inert atmosphere;
DOI:10.1021/acs.joc.5b02041

Reference yield:

: 108-42-9
3-chloro-aniline

: 59394-27-3
7-chloro-quinoline-2-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water; toluene / 1.5 h / 110 °C

1.2: 1 h / 60 °C / Cooling with ice

2.1: selenium(IV) oxide / 1,4-dioxane / 60 °C / Inert atmosphere

With hydrogenchloride; selenium(IV) oxide; In 1,4-dioxane; water; toluene;
DOI:10.1021/acs.joc.5b02041