(4-Fluoro-1-benzothiophen-2-yl)methanol

Base Information

Chemical Name:(4-Fluoro-1-benzothiophen-2-yl)methanol
CAS No.:957059-61-9
Molecular Formula:C9H7FOS
Molecular Weight:182.218
Hs Code.:2934999090
Mol file:957059-61-9.mol

Synonyms:(4-Fluoro-1-benzothiophen-2-yl)methanol;(4-fluorobenzo[b]thiophen-2-yl)methanol

Suppliers and Price of (4-Fluoro-1-benzothiophen-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(4-Fluoro-1-benzothiophen-2-yl)methanol >95%
500mg
$ 262.00

Matrix Scientific
(4-Fluoro-1-benzothiophen-2-yl)methanol >95%
1g
$ 328.00

Crysdot
(4-Fluorobenzo[b]thiophen-2-yl)methanol 95+%
5g
$ 683.00

Apolloscientific
(4-Fluoro-1-benzothiophen-2-yl)methanol 95%
1g
$ 298.00

AK Scientific
(4-Fluoro-1-benzothiophen-2-yl)methanol
1g
$ 492.00

Total 6 raw suppliers

Chemical Property of (4-Fluoro-1-benzothiophen-2-yl)methanol

Chemical Property:

PSA：48.47000
LogP:2.53270

Purity/Quality:

99%, ^*data from raw suppliers

(4-Fluoro-1-benzothiophen-2-yl)methanol >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4-Fluoro-1-benzothiophen-2-yl)methanol

There total 4 articles about (4-Fluoro-1-benzothiophen-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 220180-55-2
methyl 4-fluorobenzo[b]thiophene-2-carboxylate

: 957059-61-9
(4-fluoro-benzo[b]thiophen-2-yl)-methanol

Guidance literature:: With sodium tetrahydridoborate; ethanol; calcium(II) chloride; In tetrahydrofuran; at 25 ℃; for 5h;
DOI:10.1021/acs.oprd.1c00481

Reference yield:

: 310466-37-6
4-fluoro-1-benzothiophene-2-carboxylic acid

: 957059-61-9
(4-fluoro-benzo[b]thiophen-2-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 18 h / 20 °C

1.2: 18 h / 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C

With lithium aluminium tetrahydride; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 437-81-0
2,6-difluorobenzaldehyde

: 957059-61-9
(4-fluoro-benzo[b]thiophen-2-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 60 °C

2: sodium tetrahydridoborate; ethanol; calcium(II) chloride / tetrahydrofuran / 5 h / 25 °C

With sodium tetrahydridoborate; ethanol; potassium carbonate; calcium(II) chloride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/acs.oprd.1c00481