Methyl 4-fluoro-1-benzothiophene-2-carboxylate

Base Information

Chemical Name:Methyl 4-fluoro-1-benzothiophene-2-carboxylate
CAS No.:220180-55-2
Molecular Formula:C₁₀H₇FO₂S
Molecular Weight:210.229
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90382509
Wikidata:Q82173866
Mol file:220180-55-2.mol

Synonyms:220180-55-2;methyl 4-fluoro-1-benzothiophene-2-carboxylate;Methyl 4-fluorobenzo[b]thiophene-2-carboxylate;4-Fluoro-benzo[b]thiophene-2-carboxylic acid methyl ester;Benzo[b]thiophene-2-carboxylic acid, 4-fluoro-, methyl ester;MFCD06200964;methyl 4-fluoro-2,3-dihydrobenzo[b]thiophene-2-carboxylate;Methyl4-fluorobenzo[b]thiophene-2-carboxylate;SCHEMBL721446;DTXSID90382509;SPZLAMSTAIFDBN-UHFFFAOYSA-N;4-FLUORO-BENZO[B]THIOPHENE-2-CARBOXYLICACIDMETHYLESTER;AKOS000672414;CS-W000654;SB66957;SY239169;FT-0680399;Methyl4-fluoro-1-benzothiophene-2-carboxylate;4T-1304;methyl 4-fluoro-1-benzo[b]thiophene-2-carboxylate;J-522347;Z24634237

Suppliers and Price of Methyl 4-fluoro-1-benzothiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-Fluoro-1-benzothiophene-2-carboxylate
50mg
$ 45.00

SynQuest Laboratories
Methyl 4-fluorobenzo[b]thiophene-2-carboxylate
1 g
$ 77.00

Matrix Scientific
Methyl 4-fluoro-1-benzothiophene-2-carboxylate >95%
5g
$ 524.00

Matrix Scientific
Methyl 4-fluoro-1-benzothiophene-2-carboxylate >95%
1g
$ 228.00

Matrix Scientific
Methyl 4-fluoro-1-benzothiophene-2-carboxylate >95%
500mg
$ 181.00

Crysdot
Methyl4-fluorobenzo[b]thiophene-2-carboxylate 95+%
5g
$ 554.00

Chemenu
Methyl4-fluorobenzo[b]thiophene-2-carboxylate 95%+
5g
$ 650.00

Chemenu
Methyl4-fluorobenzo[b]thiophene-2-carboxylate 95%+
250mg
$ 90.00

Chemenu
Methyl4-fluorobenzo[b]thiophene-2-carboxylate 95%+
100mg
$ 47.00

Chemenu
Methyl4-fluorobenzo[b]thiophene-2-carboxylate 95%+
1g
$ 225.00

Total 20 raw suppliers

Chemical Property of Methyl 4-fluoro-1-benzothiophene-2-carboxylate

Chemical Property:

Vapor Pressure:0.000685mmHg at 25°C
Melting Point:96-98°
Refractive Index:1.616
Boiling Point:308.3°C at 760 mmHg
Flash Point:140.3°C
PSA：54.54000
Density:1.355g/cm³
LogP:2.82700
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:210.01507880
Heavy Atom Count:14
Complexity:234

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-Fluoro-1-benzothiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=C(C=CC=C2S1)F

Technology Process of Methyl 4-fluoro-1-benzothiophene-2-carboxylate

There total 6 articles about Methyl 4-fluoro-1-benzothiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 437-81-0
2,6-difluorobenzaldehyde

: 2365-48-2
Methyl thioglycolate

: 220180-55-2
methyl 4-fluorobenzo[b]thiophene-2-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 15h;
DOI:10.1016/j.ejmech.2019.04.024

Reference yield:

: 67-56-1
methanol

: 310466-37-6
4-fluoro-1-benzothiophene-2-carboxylic acid

: 220180-55-2
methyl 4-fluorobenzo[b]thiophene-2-carboxylate

Guidance literature:: 4-fluoro-1-benzothiophene-2-carboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 18h;

methanol; In dichloromethane; at 20 ℃; for 18h;